Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2-oxoglutarate | oxoglutarate production; substrate inhibition at high concentration | dolphin | |
L-glutamate | forward reaction, substrate L-aspartate | dolphin | |
malate | isozymes Asp-DEAE-1 and Asp-DEAE-2 | dolphin | |
oxaloacetate | substrate inhibition | dolphin | |
succinate | forward reaction | dolphin |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | - |
dolphin |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | cytosolic isoenzyme | dolphin | 5829 | - |
mitochondrion | mitochondrial isoenzyme | dolphin | 5739 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-aspartate + 2-oxoglutarate | dolphin | role in energy metabolism of diving animals | oxaloacetate + L-glutamate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
dolphin | - |
cytosolic and mitochondrial isozyme | - |
Purification (Comment) | Organism |
---|---|
cytosolic and mitochondrial isozymes | dolphin |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
muscle | - |
dolphin | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
100 | - |
purified cytosolic isozyme | dolphin |
228 | - |
purified mitochondrial isozyme | dolphin |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-aspartate + 2-oxoglutarate | - |
dolphin | oxaloacetate + L-glutamate | - |
r | |
L-aspartate + 2-oxoglutarate | role in energy metabolism of diving animals | dolphin | oxaloacetate + L-glutamate | - |
? | |
L-glutamate + 2-oxoglutarate | L-glutamate is best amino acid donor | dolphin | 2-oxoglutarate + L-glutamate | - |
? | |
L-phenylalanine + 2-oxoglutarate | - |
dolphin | 2-oxo-3-phenylpropionic acid + L-glutamate | - |
ir | |
L-tyrosine + 2-oxoglutarate | - |
dolphin | 3-(4-hydroxyphenyl)-2-oxopropionic acid + L-glutamate | - |
ir |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
6.3 | 7.3 | mitochondrial enzyme | dolphin |
7.3 | 8.3 | cytosolic enzyme | dolphin |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
6.8 | 8.3 | pH 6.8: 76% of activity maximum, pH 7.3-8.3: activity maximum, supernatant enzyme | dolphin |