BRENDA - Enzyme Database
show all sequences of 2.7.8.11

Phosphatidylinositol synthase of Tetrahymena: inositol isomers as substrates in phosphatidylinositol biosynthesis and headgroup exchange reactions

Riggs, B.M.; Lansley, T.A.; Ryals, P.E.; J. Eukaryot. Microbiol. 54, 119-124 (2007)

Data extracted from this reference:

Localization
Localization
Commentary
Organism
GeneOntology No.
Textmining
microsome
; microsomal fractions from Tetrahymena vorax, positive for NADPH-cytochrome c reductase activity
Tetrahymena vorax
-
-
Metals/Ions
Metals/Ions
Commentary
Organism
Structure
Mg2+
less effect at more than 5 mM; stimulation, maximum catalytic activity in presence of 2 mM MgCl2 plus 2 mM MnCl2. Less stimulatory above 5 mM
Tetrahymena vorax
Mn2+
greater effect than Mg2+, less effect at more than 5 mM; stimulation, maximum catalytic activity in presence of 2 mM MgCl2 plus 2 mM MnCl2. Less stimulatory above 5 mM
Tetrahymena vorax
additional information
slight or no effect by calcium, cobalt, copper, iron, lithium, molybdenum, zinc ions; synergistic effect of Mg2+ and Mn2+, optimum condition: 2 mM MgCl2, 2 mM MnCl2
Tetrahymena vorax
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Tetrahymena vorax
-
-
-
Tetrahymena vorax V2S
-
-
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
CDP-diacylglycerol + 1D-chiro-inositol
conversion of 30.9% CDP-diacylglycerol (utilization significant compared to background, p: 0.05), microsomal fraction, 30°C, 20 min
675120
Tetrahymena vorax
CMP + phosphatidyl-1D-chiro-inositol
-
-
-
?
CDP-diacylglycerol + 1L-chiro-inositol
conversion of 25.1% CDP-diacylglycerol (non-significant), microsomal fraction, 30°C, 20 min
675120
Tetrahymena vorax
CMP + phosphatidyl-1L-chiro-inositol
-
-
-
?
CDP-diacylglycerol + allo-inositol
83% of the activity on myo-inositol
675120
Tetrahymena vorax
CMP + phosphatidyl-allo-inositol
-
-
-
?
CDP-diacylglycerol + allo-inositol
conversion of 23.2% CDP-diacylglycerol (non-significant), microsomal fraction, 30°C, 20 min
675120
Tetrahymena vorax
CMP + phosphatidyl-allo-inositol
-
-
-
?
CDP-diacylglycerol + allo-inositol
83% of the activity on myo-inositol
675120
Tetrahymena vorax V2S
CMP + phosphatidyl-allo-inositol
-
-
-
?
CDP-diacylglycerol + allo-inositol
conversion of 23.2% CDP-diacylglycerol (non-significant), microsomal fraction, 30°C, 20 min
675120
Tetrahymena vorax V2S
CMP + phosphatidyl-allo-inositol
-
-
-
?
CDP-diacylglycerol + D-chiro-inositol
82% of the activity on myo-inositol
675120
Tetrahymena vorax
CMP + phosphatidyl-chiro-inositol
-
-
-
?
CDP-diacylglycerol + epi-inositol
62% of the activity on myo-inositol
675120
Tetrahymena vorax
CMP + phosphatidyl-epi-inositol
-
-
-
?
CDP-diacylglycerol + epi-inositol
conversion of 31.1% CDP-diacylglycerol (utilization significant compared to background, p: 0.01), microsomal fraction, 30°C, 20 min
675120
Tetrahymena vorax
CMP + phosphatidyl-epi-inositol
-
-
-
?
CDP-diacylglycerol + L-chiro-inositol
67% of the activity on myo-inositol
675120
Tetrahymena vorax
CMP + phosphatidyl-chiro-inositol
-
-
-
?
CDP-diacylglycerol + muco-inositol
41% of the activity on myo-inositol
675120
Tetrahymena vorax
CMP + phosphatidyl-muco-inositol
-
-
-
?
CDP-diacylglycerol + muco-inositol
conversion of 15.2% CDP-diacylglycerol (non-significant), microsomal fraction, 30°C, 20 min
675120
Tetrahymena vorax
CMP + phosphatidyl-muco-inositol
-
-
-
?
CDP-diacylglycerol + myo-inositol
myo-inositol and scyllo-inositol are preferred substrates
675120
Tetrahymena vorax
CMP + phosphatidyl-myo-inositol
-
-
-
?
CDP-diacylglycerol + myo-inositol
conversion of 37.4% CDP-diacylglycerol (utilization significant compared to background, p: 0.01), microsomal fraction, standard reaction: 20 min, 30°C, pH 8, 2 mM MgCl2, 2 mM MnCl2, 1.6 mM Triton X-100
675120
Tetrahymena vorax
CMP + phosphatidyl-myo-inositol
analyses by liquid scintillation counting and thin-layer chromatography
-
-
?
CDP-diacylglycerol + scyllo-inositol
myo-inositol and scyllo-inositol are preferred substrates
675120
Tetrahymena vorax
CMP + phosphatidyl-scyllo-inositol
-
-
-
?
CDP-diacylglycerol + scyllo-inositol
conversion of 33.7% CDP-diacylglycerol (utilization significant compared to background, p: 0.01), microsomal fraction, 30°C, 20 min
675120
Tetrahymena vorax
CMP + phosphatidyl-scyllo-inositol
-
-
-
?
additional information
formation of novel non-myo-inositol-containing second messengers, preferred non-myo-inositols are scyllo- and chiro-inositol
675120
Tetrahymena vorax
?
-
-
-
?
additional information
microsomal fraction contains additional PdtIn: inositol phosphatidyl transferase activity (inositol headgroup exchange, 20 min, 30°C) between myo-, scyllo-, 1D-chiro-inositol and phosphatidyl-myo-inositol, increased in presence of CMP, least specificity for 1L-chiro- and muco-inositol
675120
Tetrahymena vorax
?
-
-
-
-
additional information
myo- and scyllo-inositol preferred inositol isomers for PtdIn synthase activity, least specificity for muco-inositol
675120
Tetrahymena vorax
?
-
-
-
-
additional information
formation of novel non-myo-inositol-containing second messengers, preferred non-myo-inositols are scyllo- and chiro-inositol
675120
Tetrahymena vorax V2S
?
-
-
-
?
additional information
microsomal fraction contains additional PdtIn: inositol phosphatidyl transferase activity (inositol headgroup exchange, 20 min, 30°C) between myo-, scyllo-, 1D-chiro-inositol and phosphatidyl-myo-inositol, increased in presence of CMP, least specificity for 1L-chiro- and muco-inositol
675120
Tetrahymena vorax V2S
?
-
-
-
-
additional information
myo- and scyllo-inositol preferred inositol isomers for PtdIn synthase activity, least specificity for muco-inositol
675120
Tetrahymena vorax V2S
?
-
-
-
-
Temperature Optimum [°C]
Temperature Optimum [°C]
Temperature Optimum Maximum [°C]
Commentary
Organism
30
-
; pH 7.8
Tetrahymena vorax
Temperature Range [°C]
Temperature Minimum [°C]
Temperature Maximum [°C]
Commentary
Organism
50
-
89% of maximum activity, pH 7.8, 10 min preincubation
Tetrahymena vorax
60
-
82% of maximum activity, pH 7.8, 10 min preincubation
Tetrahymena vorax
70
-
79% of maximum activity, pH 7.8, 10 min preincubation
Tetrahymena vorax
Temperature Stability [°C]
Temperature Stability Minimum [°C]
Temperature Stability Maximum [°C]
Commentary
Organism
70
-
10 min, 80% residual activity
Tetrahymena vorax
pH Optimum
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
7.8
-
; 30°C
Tetrahymena vorax
pH Range
pH Minimum
pH Maximum
Commentary
Organism
7.3
8.4
30°C, 90% of maximum activity; about 90% of maximum activity within this range
Tetrahymena vorax
Localization (protein specific)
Localization
Commentary
Organism
GeneOntology No.
Textmining
microsome
; microsomal fractions from Tetrahymena vorax, positive for NADPH-cytochrome c reductase activity
Tetrahymena vorax
-
-
Metals/Ions (protein specific)
Metals/Ions
Commentary
Organism
Structure
Mg2+
less effect at more than 5 mM; stimulation, maximum catalytic activity in presence of 2 mM MgCl2 plus 2 mM MnCl2. Less stimulatory above 5 mM
Tetrahymena vorax
Mn2+
greater effect than Mg2+, less effect at more than 5 mM; stimulation, maximum catalytic activity in presence of 2 mM MgCl2 plus 2 mM MnCl2. Less stimulatory above 5 mM
Tetrahymena vorax
additional information
slight or no effect by calcium, cobalt, copper, iron, lithium, molybdenum, zinc ions; synergistic effect of Mg2+ and Mn2+, optimum condition: 2 mM MgCl2, 2 mM MnCl2
Tetrahymena vorax
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
CDP-diacylglycerol + 1D-chiro-inositol
conversion of 30.9% CDP-diacylglycerol (utilization significant compared to background, p: 0.05), microsomal fraction, 30°C, 20 min
675120
Tetrahymena vorax
CMP + phosphatidyl-1D-chiro-inositol
-
-
-
?
CDP-diacylglycerol + 1L-chiro-inositol
conversion of 25.1% CDP-diacylglycerol (non-significant), microsomal fraction, 30°C, 20 min
675120
Tetrahymena vorax
CMP + phosphatidyl-1L-chiro-inositol
-
-
-
?
CDP-diacylglycerol + allo-inositol
83% of the activity on myo-inositol
675120
Tetrahymena vorax
CMP + phosphatidyl-allo-inositol
-
-
-
?
CDP-diacylglycerol + allo-inositol
conversion of 23.2% CDP-diacylglycerol (non-significant), microsomal fraction, 30°C, 20 min
675120
Tetrahymena vorax
CMP + phosphatidyl-allo-inositol
-
-
-
?
CDP-diacylglycerol + allo-inositol
83% of the activity on myo-inositol
675120
Tetrahymena vorax V2S
CMP + phosphatidyl-allo-inositol
-
-
-
?
CDP-diacylglycerol + allo-inositol
conversion of 23.2% CDP-diacylglycerol (non-significant), microsomal fraction, 30°C, 20 min
675120
Tetrahymena vorax V2S
CMP + phosphatidyl-allo-inositol
-
-
-
?
CDP-diacylglycerol + D-chiro-inositol
82% of the activity on myo-inositol
675120
Tetrahymena vorax
CMP + phosphatidyl-chiro-inositol
-
-
-
?
CDP-diacylglycerol + epi-inositol
62% of the activity on myo-inositol
675120
Tetrahymena vorax
CMP + phosphatidyl-epi-inositol
-
-
-
?
CDP-diacylglycerol + epi-inositol
conversion of 31.1% CDP-diacylglycerol (utilization significant compared to background, p: 0.01), microsomal fraction, 30°C, 20 min
675120
Tetrahymena vorax
CMP + phosphatidyl-epi-inositol
-
-
-
?
CDP-diacylglycerol + L-chiro-inositol
67% of the activity on myo-inositol
675120
Tetrahymena vorax
CMP + phosphatidyl-chiro-inositol
-
-
-
?
CDP-diacylglycerol + muco-inositol
41% of the activity on myo-inositol
675120
Tetrahymena vorax
CMP + phosphatidyl-muco-inositol
-
-
-
?
CDP-diacylglycerol + muco-inositol
conversion of 15.2% CDP-diacylglycerol (non-significant), microsomal fraction, 30°C, 20 min
675120
Tetrahymena vorax
CMP + phosphatidyl-muco-inositol
-
-
-
?
CDP-diacylglycerol + myo-inositol
myo-inositol and scyllo-inositol are preferred substrates
675120
Tetrahymena vorax
CMP + phosphatidyl-myo-inositol
-
-
-
?
CDP-diacylglycerol + myo-inositol
conversion of 37.4% CDP-diacylglycerol (utilization significant compared to background, p: 0.01), microsomal fraction, standard reaction: 20 min, 30°C, pH 8, 2 mM MgCl2, 2 mM MnCl2, 1.6 mM Triton X-100
675120
Tetrahymena vorax
CMP + phosphatidyl-myo-inositol
analyses by liquid scintillation counting and thin-layer chromatography
-
-
?
CDP-diacylglycerol + scyllo-inositol
myo-inositol and scyllo-inositol are preferred substrates
675120
Tetrahymena vorax
CMP + phosphatidyl-scyllo-inositol
-
-
-
?
CDP-diacylglycerol + scyllo-inositol
conversion of 33.7% CDP-diacylglycerol (utilization significant compared to background, p: 0.01), microsomal fraction, 30°C, 20 min
675120
Tetrahymena vorax
CMP + phosphatidyl-scyllo-inositol
-
-
-
?
additional information
formation of novel non-myo-inositol-containing second messengers, preferred non-myo-inositols are scyllo- and chiro-inositol
675120
Tetrahymena vorax
?
-
-
-
?
additional information
microsomal fraction contains additional PdtIn: inositol phosphatidyl transferase activity (inositol headgroup exchange, 20 min, 30°C) between myo-, scyllo-, 1D-chiro-inositol and phosphatidyl-myo-inositol, increased in presence of CMP, least specificity for 1L-chiro- and muco-inositol
675120
Tetrahymena vorax
?
-
-
-
-
additional information
myo- and scyllo-inositol preferred inositol isomers for PtdIn synthase activity, least specificity for muco-inositol
675120
Tetrahymena vorax
?
-
-
-
-
additional information
formation of novel non-myo-inositol-containing second messengers, preferred non-myo-inositols are scyllo- and chiro-inositol
675120
Tetrahymena vorax V2S
?
-
-
-
?
additional information
microsomal fraction contains additional PdtIn: inositol phosphatidyl transferase activity (inositol headgroup exchange, 20 min, 30°C) between myo-, scyllo-, 1D-chiro-inositol and phosphatidyl-myo-inositol, increased in presence of CMP, least specificity for 1L-chiro- and muco-inositol
675120
Tetrahymena vorax V2S
?
-
-
-
-
additional information
myo- and scyllo-inositol preferred inositol isomers for PtdIn synthase activity, least specificity for muco-inositol
675120
Tetrahymena vorax V2S
?
-
-
-
-
Temperature Optimum [°C] (protein specific)
Temperature Optimum [°C]
Temperature Optimum Maximum [°C]
Commentary
Organism
30
-
; pH 7.8
Tetrahymena vorax
Temperature Range [°C] (protein specific)
Temperature Minimum [°C]
Temperature Maximum [°C]
Commentary
Organism
50
-
89% of maximum activity, pH 7.8, 10 min preincubation
Tetrahymena vorax
60
-
82% of maximum activity, pH 7.8, 10 min preincubation
Tetrahymena vorax
70
-
79% of maximum activity, pH 7.8, 10 min preincubation
Tetrahymena vorax
Temperature Stability [°C] (protein specific)
Temperature Stability Minimum [°C]
Temperature Stability Maximum [°C]
Commentary
Organism
70
-
10 min, 80% residual activity
Tetrahymena vorax
pH Optimum (protein specific)
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
7.8
-
; 30°C
Tetrahymena vorax
pH Range (protein specific)
pH Minimum
pH Maximum
Commentary
Organism
7.3
8.4
30°C, 90% of maximum activity; about 90% of maximum activity within this range
Tetrahymena vorax
Other publictions for EC 2.7.8.11
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
737766
Bochud
The active site of yeast phosp ...
Saccharomyces cerevisiae, Saccharomyces cerevisiae BY4742
Biochim. Biophys. Acta
1851
629-640
2015
-
-
1
-
3
-
2
-
3
1
-
4
-
3
-
-
1
-
-
-
-
-
4
-
1
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
3
-
-
2
-
-
3
1
-
4
-
-
-
1
-
-
-
-
4
-
1
-
-
-
1
-
-
-
-
3
3
-
-
-
726887
Morii
Ubiquitous distribution of pho ...
Homo sapiens, Saccharomyces cerevisiae
Biochem. Biophys. Res. Commun.
443
86-90
2013
-
-
-
-
2
-
-
-
-
2
-
2
-
13
-
-
-
-
-
-
-
-
4
-
2
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-
-
2
-
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-
-
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-
-
2
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2
-
2
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-
4
-
2
-
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-
2
-
-
-
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2
2
-
-
-
739273
Liu
Overexpression of the phosphat ...
Zea mays, Zea mays DH4866
Plant Cell Environ.
36
1037-1055
2013
-
-
1
-
1
-
-
-
2
-
-
2
-
4
-
-
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-
-
1
-
-
2
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1
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1
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2
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2
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1
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2
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-
-
-
-
-
-
3
3
-
-
-
726251
Zhai
Overexpression of the phosphat ...
Zea mays
Planta
235
69-84
2012
-
-
1
-
-
-
-
-
2
-
1
-
-
5
-
-
-
-
-
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-
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1
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2
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1
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-
-
-
-
-
-
-
-
-
-
-
-
-
1
1
-
-
-
724923
Murphy
Phosphatidylinositol synthase ...
Danio rerio
Exp. Eye Res.
93
460-474
2011
-
-
-
-
1
-
-
-
-
-
-
-
-
3
-
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-
-
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3
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1
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3
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-
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-
-
1
1
-
-
-
726195
Davy de Virville
Assessment of mitochondria as ...
Solanum tuberosum
Plant Physiol. Biochem.
48
952-960
2010
-
-
-
-
-
-
-
-
2
-
-
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3
-
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1
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2
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1
-
-
-
-
-
-
-
-
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-
690824
Loefke
Alternative metabolic fates of ...
Arabidopsis thaliana
Biochem. J.
413
115-124
2008
-
-
1
-
1
-
-
-
3
-
-
2
-
5
-
-
1
-
-
1
-
-
18
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
1
-
-
-
-
-
6
-
-
2
-
-
-
2
-
2
-
-
18
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
675120
Riggs
Phosphatidylinositol synthase ...
Tetrahymena vorax, Tetrahymena vorax V2S
J. Eukaryot. Microbiol.
54
119-124
2007
-
-
-
-
-
-
-
-
1
3
-
-
-
4
-
-
-
-
-
-
-
-
22
-
1
3
1
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
3
-
-
-
-
-
-
-
-
-
-
22
-
1
3
1
-
1
1
-
-
-
-
-
-
-
-
677090
Wengelnik
Characterisation of the phosph ...
Plasmodium falciparum, Plasmodium knowlesi
Res. Microbiol.
158
51-59
2007
-
-
2
-
3
-
-
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2
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4
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8
-
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-
-
-
3
-
2
2
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2
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671861
Martin
Phosphatidylinositol synthesis ...
Trypanosoma brucei
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662396
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Regulation of the PIS1-encoded ...
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663187
Das
Cloning of Brassica napus phos ...
Brassica napus
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645324
Blouin
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Membrane lipid biosynthesis in ...
Chlamydomonas reinhardtii
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41
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2003
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2
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1
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4
1
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3
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1
1
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2
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645325
Justin
Synthetic capacity of Arabidop ...
Arabidopsis thaliana
Biochim. Biophys. Acta
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2003
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1
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645321
Deguchi
Overexpression of phosphatidyl ...
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157-166
2002
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2
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645322
Justin
Phosphatidylinositol synthesis ...
Arabidopsis thaliana, no activity in Escherichia coli
Eur. J. Biochem.
269
2347-2352
2002
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1
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7
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2
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645323
Norman
Crystal structure of inositol ...
Mycobacterium tuberculosis
Structure
10
393-402
2002
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1
1
1
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1
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1
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645319
Seron
Molecular cloning, functional ...
Toxoplasma gondii, Toxoplasma gondii 76K
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267
6571-6579
2000
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1
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2
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1
2
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2
1
2
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2
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645320
Xue
Cloning of Arabidopsis thalian ...
Arabidopsis thaliana, no activity in Saccharomyces cerevisiae
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42
757-764
2000
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1
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1
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2
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1
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1
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1
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643323
Lykidis
The role of CDP-diacylglycerol ...
Homo sapiens
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272
33402-33409
1997
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645316
Antonsson
Phosphatidylinositol synthase ...
Bos taurus, Cavia porcellus, Gallus gallus, Homo sapiens, Meleagris gallopavo, Oryctolagus cuniculus, Rattus norvegicus, Saccharomyces cerevisiae
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179-186
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1
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11
2
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19
12
5
8
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3
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20
2
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13
2
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1
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645318
Nikawa
Phosphatidylinositol synthase ...
no activity in Escherichia coli, Rattus norvegicus, Saccharomyces cerevisiae
Biochim. Biophys. Acta
1348
173-178
1997
2
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2
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2
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4
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2
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645315
Antonsson
Candida albicans phosphatidyli ...
Candida albicans
Yeast
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3
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1
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14
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3
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1
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1
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645314
Justin
Compared selectivities of the ...
Zea mays
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645311
Antonsson
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Purification and characterizat ...
Homo sapiens
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13
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13
1
4
2
1
1
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1
1
4
3
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1
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1
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2
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645312
Elabbadi
Characterization of phosphatid ...
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2
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1
1
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1
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645313
Monaco
-
Identification of rat liver ph ...
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1
1
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645310
Klezovitch
Characterization of reactions ...
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3
1
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1
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4
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1
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1
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2
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3
1
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645308
Carman
Phosphatidylinositol synthase ...
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305-312
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1
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1
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1
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1
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645309
Imoto
Inhibition of CDP-DG: inositol ...
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1
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645307
Cubitt
Characterization of a salt-ext ...
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2
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1
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1
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1
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2
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2
4
2
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1
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1
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1
1
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1
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1
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645306
Kasinathan
Presence of a Ca2+-sensitive C ...
Canis lupus familiaris
Biochemistry
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2834-2839
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1
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1
1
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1
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5
2
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1
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1
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-
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1
1
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645305
Fischl
Phosphatidylinositol synthase ...
Saccharomyces cerevisiae
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1
1
1
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1
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2
2
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1
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1
1
1
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1
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645304
Parries
Inhibition of phosphatidylinos ...
Canis lupus familiaris
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1
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2
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1
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1
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1
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-
-
-
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-
-
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645303
Parries
Phosphatidylinositol synthase ...
Canis lupus familiaris
Biochemistry
23
4785-4791
1984
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-
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2
3
3
2
2
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2
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1
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2
2
2
3
1
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2
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2
3
3
2
2
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1
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2
2
2
3
1
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-
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2
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645302
Fischl
Phosphatidylinositol biosynthe ...
Saccharomyces cerevisiae
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304-311
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5
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1
1
2
1
1
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1
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1
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1
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1
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5
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3
2
1
1
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1
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1
1
2
1
1
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1
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1
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210005
Murthy
Stereospecific synthesis and e ...
Cavia porcellus
Biochim. Biophys. Acta
712
473-483
1982
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1
4
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1
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7
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1
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1
1
4
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1
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1
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7
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-
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645301
Robinson
Solubilization of microsomal-a ...
Glycine max
Plant Physiol.
69
146-149
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1
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2
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1
2
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1
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1
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1
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1
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2
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1
2
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1
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-
645299
Bleasdale
Characterization of the forwar ...
Oryctolagus cuniculus
Biochim. Biophys. Acta
575
135-147
1979
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1
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1
2
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2
1
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6
-
3
1
2
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1
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1
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