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Literature summary for 2.8.1.3 extracted from

  • Chauncey, T.R.; Westley, J.
    The catalytic mechanism of yeast thiosulfate reductase (1983), J. Biol. Chem., 258, 15037-15045.
    View publication on PubMed
Search for more literature for 2.8.1.3

Inhibitors

Inhibitors Comment Organism Structure
benzene sulfinate competitive with both substrates Saccharomyces cerevisiae
sulfate non-competitive inhibition when glutathione is the varied substrate Saccharomyces cerevisiae
sulfite competitive inhibition when glutathione is the varied substrate Saccharomyces cerevisiae

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.24
-
 Benzenethiosulfonate pH 8.1, 37°C Saccharomyces cerevisiae
0.89
-
 glutathione pH 8.1, 37°C, with benzenethiosulfonate as the other substrate Saccharomyces cerevisiae
2.9
-
 thiosulfate pH 8.1, 37°C Saccharomyces cerevisiae
4
-
 glutathione pH 8.1, 37°C, with thiosulfate as the other substrate Saccharomyces cerevisiae

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
thiosulfate + glutathione Saccharomyces cerevisiae
-
 sulfite + glutathione disulfide + sulfide
-
 ?

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
-
 Red Star brand
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
benzenethiosulfonate + glutathione rapid equilibrium-ordered mechanism with glutathione as leading substrate Saccharomyces cerevisiae additional information glutathione persulfide as an immediate product ?
thiosulfate + glutathione
-
 Saccharomyces cerevisiae sulfite + glutathione disulfide + sulfide
-
 ?
thiosulfate + glutathione
-
 Saccharomyces cerevisiae sulfite + glutathione disulfide + sulfide the primary product is glutathione hydrodisulfide, which reacts with glutathione to give oxidized glutathione and sulfide ?