Activating Compound | Comment | Organism | Structure |
---|---|---|---|
di(2-ethylhexyl)phthalate | induced by di(2-ethylhexyl)phthalate | Mus musculus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
endoplasmic reticulum | - |
Homo sapiens | 5783 | - |
microsome | - |
Cavia porcellus | - |
- |
microsome | - |
Mus musculus | - |
- |
microsome | - |
Rattus norvegicus | - |
- |
microsome | - |
Canis lupus familiaris | - |
- |
microsome | - |
Mesocricetus auratus | - |
- |
microsome | - |
Homo sapiens | - |
- |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Canis lupus familiaris | - |
- |
- |
Cavia porcellus | - |
- |
- |
Homo sapiens | P23141 | - |
- |
Mesocricetus auratus | - |
- |
- |
Mus musculus | - |
- |
- |
Rattus norvegicus | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
glycoprotein | most CES isozymes are glycoproteins, and the carbohydrate chain is required for the enzyme activity | Cavia porcellus |
glycoprotein | most CES isozymes are glycoproteins, and the carbohydrate chain is required for the enzyme activity | Mus musculus |
glycoprotein | most CES isozymes are glycoproteins, and the carbohydrate chain is required for the enzyme activity | Rattus norvegicus |
glycoprotein | most CES isozymes are glycoproteins, and the carbohydrate chain is required for the enzyme activity | Canis lupus familiaris |
glycoprotein | most CES isozymes are glycoproteins, and the carbohydrate chain is required for the enzyme activity | Mesocricetus auratus |
glycoprotein | most CES isozymes are glycoproteins, and the carbohydrate chain is required for the enzyme activity | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
kidney | CES1 and CES2 are strongly expressed in liver | Mus musculus | - |
kidney | CES1 but not CES2 is strongly expressed in kidney | Rattus norvegicus | - |
kidney | CES1 but not CES2 is strongly expressed in kidney | Mesocricetus auratus | - |
kidney | predominant expression of CES1 in kidney | Cavia porcellus | - |
kidney | predominant expression of isozyme CES2 | Homo sapiens | - |
liver | CES1 and CES2 are expressed in liver | Canis lupus familiaris | - |
liver | CES1 and CES2 are strongly expressed in liver | Mus musculus | - |
liver | CES1 but not CES2 is expressed in liver | Cavia porcellus | - |
liver | CES1 but not CES2 is strongly expressed in liver | Rattus norvegicus | - |
liver | CES1 but not CES2 is strongly expressed in liver | Mesocricetus auratus | - |
liver | most of all CES1 family, except CES1G, are mainly expressed in liver | Homo sapiens | - |
lung | CES1 but not CES2 is strongly expressed in lung | Rattus norvegicus | - |
lung | predominant expression of CES1 in lung | Canis lupus familiaris | - |
lung | predominant expression of isozyme CES1 | Mus musculus | - |
lung | predominant expression of isozyme CES1 | Homo sapiens | - |
additional information | not detected in small intestine | Canis lupus familiaris | - |
additional information | not expressed in lung | Mesocricetus auratus | - |
small intestine | CES2 but not CES1 is strongly expressed in small intestine | Rattus norvegicus | - |
small intestine | CES2 but not CES1 is strongly expressed in small intestine | Mesocricetus auratus | - |
small intestine | predominant expression of CES1 in small intestine | Cavia porcellus | - |
small intestine | predominant expression of isozyme CES2 | Mus musculus | - |
small intestine | predominant expression of isozyme CES2 | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
4-nitrophenyl acetate + H2O | - |
Cavia porcellus | 4-nitrophenol + acetate | - |
? | |
4-nitrophenyl acetate + H2O | - |
Mus musculus | 4-nitrophenol + acetate | - |
? | |
4-nitrophenyl acetate + H2O | - |
Rattus norvegicus | 4-nitrophenol + acetate | - |
? | |
4-nitrophenyl acetate + H2O | - |
Canis lupus familiaris | 4-nitrophenol + acetate | - |
? | |
4-nitrophenyl acetate + H2O | - |
Mesocricetus auratus | 4-nitrophenol + acetate | - |
? | |
4-nitrophenyl acetate + H2O | - |
Homo sapiens | 4-nitrophenol + acetate | - |
? | |
capecitabin + H2O | - |
Cavia porcellus | ? | - |
? | |
capecitabin + H2O | - |
Mus musculus | ? | - |
? | |
capecitabin + H2O | - |
Rattus norvegicus | ? | - |
? | |
capecitabin + H2O | - |
Canis lupus familiaris | ? | - |
? | |
capecitabin + H2O | - |
Mesocricetus auratus | ? | - |
? | |
capecitabin + H2O | - |
Homo sapiens | ? | - |
? | |
cilazapril + H2O | - |
Cavia porcellus | ? | - |
? | |
cilazapril + H2O | - |
Mus musculus | ? | - |
? | |
cilazapril + H2O | - |
Rattus norvegicus | ? | - |
? | |
cilazapril + H2O | - |
Canis lupus familiaris | ? | - |
? | |
cilazapril + H2O | - |
Mesocricetus auratus | ? | - |
? | |
cilazapril + H2O | - |
Homo sapiens | ? | - |
? | |
cocaine + H2O | specific substrate for isozyme CES1 | Cavia porcellus | ecgonine methyl ester + benzoate | - |
? | |
cocaine + H2O | specific substrate for isozyme CES1 | Mus musculus | ecgonine methyl ester + benzoate | - |
? | |
cocaine + H2O | specific substrate for isozyme CES1 | Rattus norvegicus | ecgonine methyl ester + benzoate | - |
? | |
cocaine + H2O | specific substrate for isozyme CES1 | Canis lupus familiaris | ecgonine methyl ester + benzoate | - |
? | |
cocaine + H2O | specific substrate for isozyme CES1 | Mesocricetus auratus | ecgonine methyl ester + benzoate | - |
? | |
cocaine + H2O | specific substrate for isozyme CES1 | Homo sapiens | ecgonine methyl ester + benzoate | - |
? | |
cocaine + H2O | the substrate is more specific for isozyme CES2 than for CES1 | Cavia porcellus | ecgonine methyl ester + benzoate | - |
? | |
cocaine + H2O | the substrate is more specific for isozyme CES2 than for CES1 | Mus musculus | ecgonine methyl ester + benzoate | - |
? | |
cocaine + H2O | the substrate is more specific for isozyme CES2 than for CES1 | Rattus norvegicus | ecgonine methyl ester + benzoate | - |
? | |
cocaine + H2O | the substrate is more specific for isozyme CES2 than for CES1 | Canis lupus familiaris | ecgonine methyl ester + benzoate | - |
? | |
cocaine + H2O | the substrate is more specific for isozyme CES2 than for CES1 | Mesocricetus auratus | ecgonine methyl ester + benzoate | - |
? | |
cocaine + H2O | the substrate is more specific for isozyme CES2 than for CES1 | Homo sapiens | ecgonine methyl ester + benzoate | - |
? | |
CPT-11 + H2O | the substrate is more specific for isozyme CES2 than for CES1 | Cavia porcellus | SN-38 + ? | - |
? | |
CPT-11 + H2O | the substrate is more specific for isozyme CES2 than for CES1 | Mus musculus | SN-38 + ? | - |
? | |
CPT-11 + H2O | the substrate is more specific for isozyme CES2 than for CES1 | Rattus norvegicus | SN-38 + ? | - |
? | |
CPT-11 + H2O | the substrate is more specific for isozyme CES2 than for CES1 | Canis lupus familiaris | SN-38 + ? | - |
? | |
CPT-11 + H2O | the substrate is more specific for isozyme CES2 than for CES1 | Mesocricetus auratus | SN-38 + ? | - |
? | |
CPT-11 + H2O | the substrate is more specific for isozyme CES2 than for CES1 | Homo sapiens | SN-38 + ? | - |
? | |
heroin + H2O | the substrate is more specific for isozyme CES2 than for CES1 | Cavia porcellus | 6-monoacetylmorphine + acetate | - |
? | |
heroin + H2O | the substrate is more specific for isozyme CES2 than for CES1 | Mus musculus | 6-monoacetylmorphine + acetate | - |
? | |
heroin + H2O | the substrate is more specific for isozyme CES2 than for CES1 | Rattus norvegicus | 6-monoacetylmorphine + acetate | - |
? | |
heroin + H2O | the substrate is more specific for isozyme CES2 than for CES1 | Canis lupus familiaris | 6-monoacetylmorphine + acetate | - |
? | |
heroin + H2O | the substrate is more specific for isozyme CES2 than for CES1 | Mesocricetus auratus | 6-monoacetylmorphine + acetate | - |
? | |
heroin + H2O | the substrate is more specific for isozyme CES2 than for CES1 | Homo sapiens | 6-monoacetylmorphine + acetate | - |
? | |
imidapril + H2O | the substrate is more specific for isozyme CES2 than for CES1 | Cavia porcellus | ? | - |
? | |
imidapril + H2O | the substrate is more specific for isozyme CES2 than for CES1 | Mus musculus | ? | - |
? | |
imidapril + H2O | the substrate is more specific for isozyme CES2 than for CES1 | Rattus norvegicus | ? | - |
? | |
imidapril + H2O | the substrate is more specific for isozyme CES2 than for CES1 | Canis lupus familiaris | ? | - |
? | |
imidapril + H2O | the substrate is more specific for isozyme CES2 than for CES1 | Mesocricetus auratus | ? | - |
? | |
imidapril + H2O | the substrate is more specific for isozyme CES2 than for CES1 | Homo sapiens | ? | - |
? | |
meperidine + H2O | specific substrate for isozyme CES1 | Cavia porcellus | ? | - |
? | |
meperidine + H2O | specific substrate for isozyme CES1 | Mus musculus | ? | - |
? | |
meperidine + H2O | specific substrate for isozyme CES1 | Rattus norvegicus | ? | - |
? | |
meperidine + H2O | specific substrate for isozyme CES1 | Canis lupus familiaris | ? | - |
? | |
meperidine + H2O | specific substrate for isozyme CES1 | Mesocricetus auratus | ? | - |
? | |
meperidine + H2O | specific substrate for isozyme CES1 | Homo sapiens | ? | - |
? | |
methylphenidate + H2O | specific substrate for isozyme CES1 | Cavia porcellus | ? | - |
? | |
methylphenidate + H2O | specific substrate for isozyme CES1 | Mus musculus | ? | - |
? | |
methylphenidate + H2O | specific substrate for isozyme CES1 | Rattus norvegicus | ? | - |
? | |
methylphenidate + H2O | specific substrate for isozyme CES1 | Canis lupus familiaris | ? | - |
? | |
methylphenidate + H2O | specific substrate for isozyme CES1 | Mesocricetus auratus | ? | - |
? | |
methylphenidate + H2O | specific substrate for isozyme CES1 | Homo sapiens | ? | - |
? | |
methylprednisolone 21-hemisuccinate + H2O | the substrate is more specific for isozyme CES2 than for CES1 | Cavia porcellus | ? | - |
? | |
methylprednisolone 21-hemisuccinate + H2O | the substrate is more specific for isozyme CES2 than for CES1 | Mus musculus | ? | - |
? | |
methylprednisolone 21-hemisuccinate + H2O | the substrate is more specific for isozyme CES2 than for CES1 | Rattus norvegicus | ? | - |
? | |
methylprednisolone 21-hemisuccinate + H2O | the substrate is more specific for isozyme CES2 than for CES1 | Canis lupus familiaris | ? | - |
? | |
methylprednisolone 21-hemisuccinate + H2O | the substrate is more specific for isozyme CES2 than for CES1 | Mesocricetus auratus | ? | - |
? | |
methylprednisolone 21-hemisuccinate + H2O | the substrate is more specific for isozyme CES2 than for CES1 | Homo sapiens | ? | - |
? | |
oseltamivir + H2O | specific substrate for isozyme CES1 | Cavia porcellus | ? | - |
? | |
oseltamivir + H2O | specific substrate for isozyme CES1 | Mus musculus | ? | - |
? | |
oseltamivir + H2O | specific substrate for isozyme CES1 | Rattus norvegicus | ? | - |
? | |
oseltamivir + H2O | specific substrate for isozyme CES1 | Canis lupus familiaris | ? | - |
? | |
oseltamivir + H2O | specific substrate for isozyme CES1 | Mesocricetus auratus | ? | - |
? | |
oseltamivir + H2O | specific substrate for isozyme CES1 | Homo sapiens | ? | - |
? | |
quinapril + H2O | - |
Cavia porcellus | ? | - |
? | |
quinapril + H2O | - |
Mus musculus | ? | - |
? | |
quinapril + H2O | - |
Rattus norvegicus | ? | - |
? | |
quinapril + H2O | - |
Canis lupus familiaris | ? | - |
? | |
quinapril + H2O | - |
Mesocricetus auratus | ? | - |
? | |
quinapril + H2O | - |
Homo sapiens | ? | - |
? | |
temocapril + H2O | specific substrate for isozyme CES1 | Cavia porcellus | ? | - |
? | |
temocapril + H2O | specific substrate for isozyme CES1 | Mus musculus | ? | - |
? | |
temocapril + H2O | specific substrate for isozyme CES1 | Rattus norvegicus | ? | - |
? | |
temocapril + H2O | specific substrate for isozyme CES1 | Canis lupus familiaris | ? | - |
? | |
temocapril + H2O | specific substrate for isozyme CES1 | Mesocricetus auratus | ? | - |
? | |
temocapril + H2O | specific substrate for isozyme CES1 | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
acylcarnitine hydrolase | - |
Mus musculus |
CES1 | isozyme | Cavia porcellus |
CES1 | isozyme | Mus musculus |
CES1 | isozyme | Rattus norvegicus |
CES1 | isozyme | Canis lupus familiaris |
CES1 | isozyme | Mesocricetus auratus |
CES1 | isozyme | Homo sapiens |
CES2 | isozyme | Cavia porcellus |
CES2 | isozyme | Mus musculus |
CES2 | isozyme | Rattus norvegicus |
CES2 | isozyme | Canis lupus familiaris |
CES2 | isozyme | Mesocricetus auratus |
CES2 | isozyme | Homo sapiens |