Inhibitors | Comment | Organism | Structure |
---|---|---|---|
3-oxoadipate | 50% inhibition at a concentration of 17 mM; i.e. beta-ketoadipate | Acinetobacter calcoaceticus | |
3-oxoadipate | 10% inhibition at a concentration of 1 mM; 50% inhibition at a concentration of 10 mM; i.e. beta-ketoadipate | Pseudomonas putida | |
5,5'-dithiobis(2-nitrobenzoic acid) | completely inactivated, activity can not be recovered by adding dithiothreitol | Pseudomonas putida | |
additional information | not inhibited by adipate and levulinate at a concentration of 20 mM | Acinetobacter calcoaceticus | |
additional information | not inhibited by adipate and levulinate at a concentration of 20 mM | Pseudomonas putida | |
p-chloromercuribenzoate | - |
Acinetobacter calcoaceticus | |
p-chloromercuribenzoate | completely inactivated at a concentration of 0.005 mM, 95% of the activity can be recovered by addition of 10 mM dithiothreitol in the reaction mixture; inhibition can not be prevented in the presence of beta-ketoadipate | Pseudomonas putida |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
(5-oxo-4,5-dihydrofuran-2-yl)acetic acid + H2O | Pseudomonas putida | the enzyme acts on the product of EC 4.1.1.44 4-carboxymuconolactone decarboxylase | ? | - |
? | |
(5-oxo-4,5-dihydrofuran-2-yl)acetic acid + H2O | Acinetobacter calcoaceticus | the enzyme acts on the product of EC 4.1.1.44 4-carboxymuconolactone decarboxylase | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Acinetobacter calcoaceticus | - |
- |
- |
Pseudomonas putida | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
(5-oxo-4,5-dihydrofuran-2-yl)acetic acid + H2O | 3-oxoadipate enol-lactone | Pseudomonas putida | 3-oxoadipate | - |
? | |
(5-oxo-4,5-dihydrofuran-2-yl)acetic acid + H2O | 3-oxoadipate enol-lactone | Acinetobacter calcoaceticus | 3-oxoadipate | - |
? | |
(5-oxo-4,5-dihydrofuran-2-yl)acetic acid + H2O | the enzyme acts on the product of EC 4.1.1.44 4-carboxymuconolactone decarboxylase | Pseudomonas putida | ? | - |
? | |
(5-oxo-4,5-dihydrofuran-2-yl)acetic acid + H2O | the enzyme acts on the product of EC 4.1.1.44 4-carboxymuconolactone decarboxylase | Acinetobacter calcoaceticus | ? | - |
? |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
10 | - |
3-oxoadipate | - |
Pseudomonas putida | |
17 | - |
3-oxoadipate | - |
Acinetobacter calcoaceticus |