Activating Compound | Comment | Organism | Structure |
---|---|---|---|
Colipase | - |
Homo sapiens | |
sodium taurodeoxycholate | - |
Homo sapiens |
Cloned (Comment) | Organism |
---|---|
expression of PLRP2 in the protease A-deficient yeast Pichia pastoris as secreted enzyme | Homo sapiens |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | activates the phospholipase A1 activity of the enzyme, overview | Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
49946 | - |
x * 50000, recombinant enzyme, SDS-PAGE, x * 52343, recombinant glycosylated enzyme, mass spectrometry, x * 49946, recombinant nonglycosylated enzyme, mass spectrometry | Homo sapiens |
50000 | - |
x * 50000, recombinant enzyme, SDS-PAGE, x * 52343, recombinant glycosylated enzyme, mass spectrometry, x * 49946, recombinant nonglycosylated enzyme, mass spectrometry | Homo sapiens |
52343 | - |
x * 50000, recombinant enzyme, SDS-PAGE, x * 52343, recombinant glycosylated enzyme, mass spectrometry, x * 49946, recombinant nonglycosylated enzyme, mass spectrometry | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
glycoprotein | - |
Homo sapiens |
Purification (Comment) | Organism |
---|---|
recombinant secreted enzyme from protease A-deficient Pichia pastoris strain culture supernatant by cation and anion exchange chromatography to homogeneity | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
550 | - |
purified recombinant enzyme in presence of colipase at pH 8.8 | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | the enzyme also shows phospholipase A1 activity, EC 3.1.1.32, galactolipase activity, EC 3.1.1.26, and acylglycerol lipase activity, EC 3.1.1.23, overview | Homo sapiens | ? | - |
? | |
olive oil + H2O | - |
Homo sapiens | ? | - |
? | |
tributyrin + H2O | - |
Homo sapiens | dibutyrin + butyrate | - |
? | |
trioctanoin + H2O | - |
Homo sapiens | dioctanoin + octanoate | - |
? | |
triolein + H2O | - |
Homo sapiens | diolein + oleate | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 50000, recombinant enzyme, SDS-PAGE, x * 52343, recombinant glycosylated enzyme, mass spectrometry, x * 49946, recombinant nonglycosylated enzyme, mass spectrometry | Homo sapiens |
Synonyms | Comment | Organism |
---|---|---|
HPLRP2 | - |
Homo sapiens |
pancreatic lipase-related protein 2 | - |
Homo sapiens |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
8 | 9 | - |
Homo sapiens |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
additional information | - |
pH profiles of the recombinant enzyme, overview | Homo sapiens |