Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.1.3.5 extracted from

  • Lamers, J.M.J.; Heyliger, C.E.; Panagia, V.; Dhalla, N.S.
    Properties of 5-nucleotidase in rat heart sarcolemma (1983), Biochim. Biophys. Acta, 742, 568-575.
    View publication on PubMed
Search for more literature for 3.1.3.5

Inhibitors

Inhibitors Comment Organism Structure
ATP
-
 Rattus norvegicus
concanavalin A
-
 Rattus norvegicus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.035
-
 5'-AMP fraction HL, sarcolemma Rattus norvegicus
0.13
-
 5'-AMP fraction S, sarcolemma Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
plasma membrane the heart sarcolemmal membrane has two 5'-nucleotidase activities which are due to differences in the orientation. Two different catalytic sites are present at the intracellular and extracellular surface Rattus norvegicus 5886
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
5'-AMP + H2O Rattus norvegicus the enzyme is responsible for the production of adenosine in the cardiac tissue ?
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
heart sarcolemma Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5'-AMP + H2O
-
 Rattus norvegicus adenosine + phosphate
-
 ?
5'-AMP + H2O the enzyme is responsible for the production of adenosine in the cardiac tissue Rattus norvegicus ?
-
 ?

Temperature Stability [°C]

Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
60
-
 25% of the activity stable Rattus norvegicus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7 8
-
 Rattus norvegicus