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Literature summary for 3.1.4.59 extracted from

  • Griffiths, J.; ONeill, A.
    Loss of function of the GdpP protein leads to joint beta-lactam/ glycopeptide tolerance in Staphylococcus aureus (2012), Antimicrob. Agents Chemother., 56, 579-581 .
    View publication on PubMedView publication on EuropePMC

Protein Variants

Protein Variants Comment Organism
G266D natural mutation identified in a strain displaying tolerance to inhibitors of peptidoglycan biosynthesis Staphylococcus aureus
T260K natural mutation identified in a strain displaying tolerance to inhibitors of peptidoglycan biosynthesis Staphylococcus aureus

Organism

Organism UniProt Comment Textmining
Staphylococcus aureus Q2G2T6
-
-
Staphylococcus aureus NCTC 8325 Q2G2T6
-
-

Synonyms

Synonyms Comment Organism
SAOUHSC_00015 locus tag Staphylococcus aureus

General Information

General Information Comment Organism
physiological function inactivation of GdpP confers tolerance to inhibitors of peptidoglycan biosynthesis Staphylococcus aureus