Literature summary for 3.1.4.59 extracted from

Du, B.; Ji, W.; An, H.; Shi, Y.; Huang, Q.; Cheng, Y.; Fu, Q.; Wang, H.; Yan, Y.; Sun, J.
Functional analysis of c-di-AMP phosphodiesterase, GdpP, in Streptococcus suis serotype 2 (2014), Microbiol. Res., 169, 749-758 .

Search for more literature for 3.1.4.59

Organism

Organism	UniProt	Comment	Textmining
Streptococcus suis	-	-	-
Streptococcus suis serotype 2	-	-	-

Synonyms

Synonyms	Comment	Organism
gdpP	-	Streptococcus suis
SSU98_2160	-	Streptococcus suis

General Information

General Information	Comment	Organism
physiological function	disruption of gdpP increases intracellular c-di-AMP level and affects growth and increases biofilm formation. The GdpP mutant strain exhibits a significant decrease in hemolytic activity and adherence to and invasion of HEp-2 cells compared with the parental strain. Virulence genes cps2,sly, fpbs, mrp, ef and gdh display reduced expression in the gdpP mutant. In murine infection models, the GdpP mutant strain is attenuated, and impaired bacterial growth is observed in specific organs	Streptococcus suis

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)