Activating Compound | Comment | Organism | Structure |
---|---|---|---|
2-mercaptoethanol | requires reducing agents, only 67% of maximal activity is observable in absence | Homo sapiens | |
dithiothreitol | requires reducing agents, only 67% of maximal activity is observable in absence, optimal concentration 2 mM | Homo sapiens | |
phosphate | - |
Homo sapiens |
General Stability | Organism |
---|---|
moderately stable | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
p-chloromercuribenzoic acid | mM PCMB causes quantitative inhibition | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0435 | - |
5'-deoxy-5'-methylthioadenosine | - |
Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
31000 | - |
3 * 31000, postulated | Homo sapiens |
95000 | - |
gel filtration | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
5'-methylthioadenosine + H2O | Homo sapiens | - |
? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
human | - |
Purification (Comment) | Organism |
---|---|
- |
Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
placenta | - |
Homo sapiens | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
2.75 | - |
- |
Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
5'-deoxy-5'-S-adenosyl-L-cysteine + H2O | relative activity 95.2% | Homo sapiens | S-(5-deoxy-5-D-ribosyl)-L-cysteine + adenine | - |
? | |
5'-deoxy-5'-S-adenosyl-L-homocysteine + H2O | substrate analogue, relative activity 95.8% | Homo sapiens | S-(5-deoxy-5-D-ribosyl)-L-homoscysteine + adenine | - |
? | |
5'-deoxy-5'-thioethanoladenosine + H2O | relative activity 98% | Homo sapiens | ? | - |
? | |
5'-methylthioadenosine + H2O | - |
Homo sapiens | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
trimer | 3 * 31000, postulated | Homo sapiens |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
67 | - |
- |
Homo sapiens |
Temperature Minimum [°C] | Temperature Maximum [°C] | Comment | Organism |
---|---|---|---|
30 | 50 | quite stable in this range | Homo sapiens |
Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|
30 | 50 | quite stable in this range | Homo sapiens |
67 | - |
enzyme activity rapidly dropping at temperatures above | Homo sapiens |