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Literature summary for 3.3.2.9 extracted from

  • Guengerich, F.P.; Wang, P.; Mitchell, M.B.; Mason, P.S.
    Rat and human liver microsomal epoxide hydratase. Purification and evidence for the existence of multiple forms (1979), J. Biol. Chem., 254, 12248-12254.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
Metyrapone stimulates Homo sapiens
Metyrapone stimulates Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome
-
Homo sapiens
-
-
microsome
-
Rattus norvegicus
-
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
50000
-
x * 50000, SDS-PAGE Homo sapiens
50000
-
x * 50000, SDS-PAGE Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Rattus norvegicus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
multiple enzyme forms Homo sapiens
multiple enzyme forms Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
Homo sapiens
-
liver
-
Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2-chloroethylene oxide + H2O
-
Homo sapiens ?
-
?
2-chloroethylene oxide + H2O
-
Rattus norvegicus ?
-
?
3-methylcholanthrene 11,12-oxide + H2O
-
Homo sapiens ?
-
?
3-methylcholanthrene 11,12-oxide + H2O
-
Rattus norvegicus ?
-
?
benzoanthracene 5,6-oxide + H2O
-
Homo sapiens ?
-
?
benzoanthracene 5,6-oxide + H2O
-
Rattus norvegicus ?
-
?
benzopyrene 4,5-oxide + H2O
-
Homo sapiens (-)benzopyrene 4,5-dihydrodiol
-
?
benzopyrene 4,5-oxide + H2O
-
Rattus norvegicus (-)benzopyrene 4,5-dihydrodiol
-
?
benzopyrene 7,8-oxide + H2O
-
Homo sapiens ?
-
?
benzopyrene 7,8-oxide + H2O
-
Rattus norvegicus ?
-
?
dibenzanthracene 5,6-oxide + H2O
-
Homo sapiens ?
-
?
dibenzanthracene 5,6-oxide + H2O
-
Rattus norvegicus ?
-
?
styrene 7,8-oxide + H2O
-
Homo sapiens styrene glycol
-
?
styrene 7,8-oxide + H2O
-
Rattus norvegicus styrene glycol
-
?

Subunits

Subunits Comment Organism
? x * 50000, SDS-PAGE Homo sapiens
? x * 50000, SDS-PAGE Rattus norvegicus