BRENDA - Enzyme Database
show all sequences of 3.4.17.23

The novel angiotensin-converting enzyme (ACE) homolog, ACE2, is selectively expressed by adult Leydig cells of the testis

Douglas, G.C.; OBryan, M.K.; Hedger, M.P.; Lee, D.K.; Yarski, M.A.; Smith, A.I.; Lew, R.A.; Endocrinology 145, 4703-4711 (2004)

Data extracted from this reference:

Cloned(Commentary)
Cloned (Commentary)
Organism
expression of recombinant ACE2 in P-selectin-transfected Chinese hamster ovary cells
Homo sapiens
Organism
Organism
UniProt
Commentary
Textmining
Homo sapiens
Q9BYF1
angiotensin-converting enzyme 2 precursor
-
Rattus norvegicus
-
-
-
Source Tissue
Source Tissue
Commentary
Organism
Textmining
Leydig cell
ACE2 may participate in the control of the testicular function
Homo sapiens
-
Leydig cell
ACE2 may participate in the control of the testicular function
Rattus norvegicus
-
Sertoli cell
-
Homo sapiens
-
testis
ACE2 may participate in the control of the testicular function
Homo sapiens
-
testis
ACE2 may participate in the control of the testicular function
Rattus norvegicus
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
Substrate Product ID
(7-methoxycoumarin-4-yl)acetyl-APK(2,4-dinitrophenyl) + H2O
-
668418
Rattus norvegicus
(7-methoxycoumarin-4-yl)acetyl-AP + N6-(2,4-dinitrophenyl)-L-lysine
-
-
-
?
(7-methoxycoumarin-4-yl)acetyl-APK(2,4-dinitrophenyl) + H2O
-
668418
Homo sapiens
(7-methoxycoumarin-4-yl)acetyl-AP + N6-(2,4-dinitrophenyl)-L-lysine
-
-
-
?
angiotensin II + H2O
-
668418
Rattus norvegicus
angiotensin-(1-7) + Phe
-
-
-
?
angiotensin II + H2O
-
668418
Homo sapiens
angiotensin-(1-7) + Phe
-
-
-
?
Synonyms
Synonyms
Commentary
Organism
ACE2
-
Rattus norvegicus
ACE2
-
Homo sapiens
angiotensin-converting enzyme
-
Homo sapiens
angiotensin-converting enzyme
-
Rattus norvegicus
Cloned(Commentary) (protein specific)
Commentary
Organism
expression of recombinant ACE2 in P-selectin-transfected Chinese hamster ovary cells
Homo sapiens
Source Tissue (protein specific)
Source Tissue
Commentary
Organism
Textmining
Leydig cell
ACE2 may participate in the control of the testicular function
Homo sapiens
-
Leydig cell
ACE2 may participate in the control of the testicular function
Rattus norvegicus
-
Sertoli cell
-
Homo sapiens
-
testis
ACE2 may participate in the control of the testicular function
Homo sapiens
-
testis
ACE2 may participate in the control of the testicular function
Rattus norvegicus
-
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
ID
(7-methoxycoumarin-4-yl)acetyl-APK(2,4-dinitrophenyl) + H2O
-
668418
Rattus norvegicus
(7-methoxycoumarin-4-yl)acetyl-AP + N6-(2,4-dinitrophenyl)-L-lysine
-
-
-
?
(7-methoxycoumarin-4-yl)acetyl-APK(2,4-dinitrophenyl) + H2O
-
668418
Homo sapiens
(7-methoxycoumarin-4-yl)acetyl-AP + N6-(2,4-dinitrophenyl)-L-lysine
-
-
-
?
angiotensin II + H2O
-
668418
Rattus norvegicus
angiotensin-(1-7) + Phe
-
-
-
?
angiotensin II + H2O
-
668418
Homo sapiens
angiotensin-(1-7) + Phe
-
-
-
?
Other publictions for EC 3.4.17.23
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Synonyms
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)