Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | structure-based drug design of diphenyl alpha-aminoalkylphosphonates as prostate-specific antigen antagonists, overview. Molecular docking and modeling of covalent and noncovalent binding of this class of inhibitors, interactions between the lead compound and residues Thr190, Ser217, and Ser227 in the P1 pocket | Homo sapiens | |
R/S-diphenyl[N-benzyloxycarbonylamino(4-carbamoylphenyl)methyl]phosphonate | - |
Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P07288 | - |
- |
Synonyms | Comment | Organism |
---|---|---|
prostate-specific antigen | - |
Homo sapiens |
PSA | - |
Homo sapiens |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.00025 | - |
pH and temperature not specified in the publication | Homo sapiens | R/S-diphenyl[N-benzyloxycarbonylamino(4-carbamoylphenyl)methyl]phosphonate |
General Information | Comment | Organism |
---|---|---|
physiological function | the enzyme is responsible for the advancement of prostate tumor progression | Homo sapiens |