Cloned (Comment) | Organism |
---|---|
expressed in HEK-293T cells | Enterovirus C |
expressed in HEK-293T cells | coxsackievirus |
recombinant 3Cpro is expressed in Escherichia coli | Enterovirus C |
recombinant 3Cpro is expressed in Escherichia coli | coxsackievirus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
eukaryotic initiation factor + H2O | coxsackievirus | cleaveage at a single site, rabbit eIF5B is proteolytically cleaves during coxsackievirus infection of cultured cells, beginning at 3 h post-infection and increasing thereafter | eukaryotic initiation factor 1-478 + eukaryotic initiation factor 479-? | - |
? | |
eukaryotic initiation factor + H2O | Enterovirus C | cleaveage at a single site, rabbit eIF5B is proteolytically cleaves during poliovirus infection of cultured cells, beginning at 3 hours post-infection and increasing thereafter | eukaryotic initiation factor 1-478 + eukaryotic initiation factor 479-? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
coxsackievirus | - |
Coxsackie B virus (CVB) | - |
Enterovirus C | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Enterovirus C |
- |
coxsackievirus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
commercial preparation | recombinant HRV14 3Cpro | coxsackievirus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
eukaryotic initiation factor + H2O | cleaveage at a single site, rabbit eIF5B is proteolytically cleaves during coxsackievirus infection of cultured cells, beginning at 3 h post-infection and increasing thereafter | coxsackievirus | eukaryotic initiation factor 1-478 + eukaryotic initiation factor 479-? | - |
? | |
eukaryotic initiation factor + H2O | cleaveage at a single site, rabbit eIF5B is proteolytically cleaves during poliovirus infection of cultured cells, beginning at 3 hours post-infection and increasing thereafter | Enterovirus C | eukaryotic initiation factor 1-478 + eukaryotic initiation factor 479-? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
3C protease | - |
Enterovirus C |
3C protease | - |
coxsackievirus |
3Cpro | - |
Enterovirus C |
3Cpro | - |
coxsackievirus |
picornain 3C | - |
Enterovirus C |
picornain 3C | - |
coxsackievirus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.5 | - |
assay at, 150 mM NaCl, 50 mM Tris-HCl | Enterovirus C |
7.5 | - |
assay at, 150 mM NaCl, 50 mM Tris-HCl | coxsackievirus |