Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Synonyms | Comment | Organism |
---|---|---|
arginine deiminase | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
malfunction | argininosuccinate synthetase-deficient SCLC cells demonstrate sensitivity to pegylated ADI (ADI-PEG20), which is associated with the induction of autophagy and caspasein-dependent cell death. Arginine deiminase-PEG20 treatment of ASS-negative SCLC xenografts causes significant, dose-dependent inhibition of tumour growth of both small and established tumours | Homo sapiens |