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Literature summary for 4.1.1.107 extracted from

  • Vavricka, C.; Han, Q.; Huang, Y.; Erickson, S.M.; Harich, K.; Christensen, B.M.; Li, J.
    From L-Dopa to dihydroxyphenylacetaldehyde a toxic biochemical pathway plays a vital physiological function in insects (2011), PLoS ONE, 6, e16124 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 4.1.1.107

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-Dopa + O2 + H2O Drosophila melanogaster
-
 3,4-dihydroxyphenylacetaldehyde + CO2 + NH3 + H2O2
-
 ?
L-Dopa + O2 + H2O Culex quinquefasciatus
-
 3,4-dihydroxyphenylacetaldehyde + CO2 + NH3 + H2O2
-
 ?
L-Dopa + O2 + H2O Anopheles gambiae
-
 3,4-dihydroxyphenylacetaldehyde + CO2 + NH3 + H2O2
-
 ?

Organism

Organism UniProt Comment Textmining
Anopheles gambiae
-
-
-
Culex quinquefasciatus
-
-
-
Drosophila melanogaster
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
alpha-methyl-L-Dopa + O2 + H2O 10-12% activity compared to L-Dopa Drosophila melanogaster 3,4-dihydroxyphenylacetone + CO2 + NH3 + H2O2
-
 ?
alpha-methyl-L-Dopa + O2 + H2O 10-12% activity compared to L-Dopa Culex quinquefasciatus 3,4-dihydroxyphenylacetone + CO2 + NH3 + H2O2
-
 ?
alpha-methyl-L-Dopa + O2 + H2O 10-12% activity compared to L-Dopa Anopheles gambiae 3,4-dihydroxyphenylacetone + CO2 + NH3 + H2O2
-
 ?
L-Dopa + O2 + H2O
-
 Drosophila melanogaster 3,4-dihydroxyphenylacetaldehyde + CO2 + NH3 + H2O2
-
 ?
L-Dopa + O2 + H2O
-
 Culex quinquefasciatus 3,4-dihydroxyphenylacetaldehyde + CO2 + NH3 + H2O2
-
 ?
L-Dopa + O2 + H2O
-
 Anopheles gambiae 3,4-dihydroxyphenylacetaldehyde + CO2 + NH3 + H2O2
-
 ?

Synonyms

Synonyms Comment Organism
DHPAA synthase
-
 Drosophila melanogaster
DHPAA synthase
-
 Culex quinquefasciatus
DHPAA synthase
-
 Anopheles gambiae
EAT37246
-
 Drosophila melanogaster
EAT37246
-
 Culex quinquefasciatus
EAT37246
-
 Anopheles gambiae

Cofactor

Cofactor Comment Organism Structure
pyridoxal 5'-phosphate
-
 Drosophila melanogaster
pyridoxal 5'-phosphate
-
 Culex quinquefasciatus
pyridoxal 5'-phosphate
-
 Anopheles gambiae

General Information

General Information Comment Organism
physiological function the enzyme plays a role in the formation of colorless, flexible cuticle Drosophila melanogaster
physiological function the enzyme plays a role in the formation of colorless, flexible cuticle Culex quinquefasciatus
physiological function the enzyme plays a role in the formation of colorless, flexible cuticle Anopheles gambiae