Application | Comment | Organism |
---|---|---|
medicine | essential role of enzyme in embryonic development, polyamines are required for cell proliferation after E3.5 | Mus musculus |
Protein Variants | Comment | Organism |
---|---|---|
additional information | targeted disruption of enzyme gene, heterozygous animals were viable, normal and fertile, homozygous embryos died early in embryonic development, homozygous blastocysts at E3.5 arrested cell proliferation which was rescued by addition of spermidine | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
enzyme is essential for embryonic development | - |