Cloned (Comment) | Organism |
---|---|
expression in Escherichia coli | Toxoplasma gondii |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0000262 | - |
26-bp-oligonucleotide | pH 7.5, 37°C | Toxoplasma gondii |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
nucleus | - |
Toxoplasma gondii | 5634 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | APN is active in presence and in absence of Mg2+ | Toxoplasma gondii |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
51000 | - |
x * 51000, SDS-PAGE | Toxoplasma gondii |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Toxoplasma gondii | F6KAZ5 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
26-bp-oligonucleotide | oligonucleotide containing a 5'-hexachloro-fluorescein phosphoramidite-labeled tetrahydrofuranyl residue in the middle | Toxoplasma gondii | 5'-hexachloro-fluorescein phosphoramidite-labeled 13-mer fragment + ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 51000, SDS-PAGE | Toxoplasma gondii |
Synonyms | Comment | Organism |
---|---|---|
APN | - |
Toxoplasma gondii |
APN1 | - |
Toxoplasma gondii |
General Information | Comment | Organism |
---|---|---|
physiological function | over-expression of APN in Toxoplasma gondii confers protection from DNA damage, and viable knockouts of APN are not obtainable. An inducible APN knockdown mutant demonstrates that APN is critical for Toxoplasma to recover from DNA damage | Toxoplasma gondii |