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Literature summary for 6.2.1.1 extracted from

  • Tucker, A.C.; Escalante-Semerena, J.C.
    Determinants within the C-terminal domain of Streptomyces lividans acetyl-CoA synthetase that block acetylation of its active site lysine in vitro by the protein acetyltransferase (Pat) enzyme (2014), PLoS ONE, 9, e99817 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 6.2.1.1

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli C41(DE3) cells Salmonella enterica
expressed in Escherichia coli C41(DE3) cells Streptomyces lividans

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + acetate + CoA Salmonella enterica
-
 AMP + diphosphate + acetyl-CoA
-
 ?
ATP + acetate + CoA Streptomyces lividans
-
 AMP + diphosphate + acetyl-CoA
-
 ?

Organism

Organism UniProt Comment Textmining
Salmonella enterica
-
-
-
Streptomyces lividans
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
acetylation
-
 Salmonella enterica
acetylation the enzyme is poorly acetylated in vitro by the Streptomyces lividans protein acetyltransferase Pat Streptomyces lividans

Purification (Commentary)

Purification (Comment) Organism
-
 Salmonella enterica
-
 Streptomyces lividans

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + acetate + CoA
-
 Salmonella enterica AMP + diphosphate + acetyl-CoA
-
 ?
ATP + acetate + CoA
-
 Streptomyces lividans AMP + diphosphate + acetyl-CoA
-
 ?

Synonyms

Synonyms Comment Organism
Acetyl-CoA synthetase
-
 Salmonella enterica
Acetyl-CoA synthetase
-
 Streptomyces lividans
ACS
-
 Salmonella enterica
ACS
-
 Streptomyces lividans
Acyl-CoA synthetase
-
 Salmonella enterica
Acyl-CoA synthetase
-
 Streptomyces lividans
AMP-forming CoA ligase
-
 Salmonella enterica
AMP-forming CoA ligase
-
 Streptomyces lividans

Cofactor

Cofactor Comment Organism Structure
ATP
-
 Salmonella enterica
ATP
-
 Streptomyces lividans