Literature summary for 7.1.1.5 extracted from

Moosa, A.; Lamprecht, D.A.; Arora, K.; Barry, C.E.; Boshoff, H.I.M.; Ioerger, T.R.; Steyn, A.J.C.; Mizrahi, V.; Warner, D.F.
Susceptibility of Mycobacterium tuberculosis cytochrome bd oxidase mutants to compounds targeting the terminal respiratory oxidase, cytochrome c (2017), Antimicrob. Agents Chemother., 61, e01338 .

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Organism

Organism	UniProt	Comment	Textmining
Mycobacterium tuberculosis	L7N662 and O06139	L7N662 i.e. subunit cydA, O06139 i.e. subunit cydB	-
Mycobacterium tuberculosis H37Rv	L7N662 and O06139	L7N662 i.e. subunit cydA, O06139 i.e. subunit cydB	-

General Information

General Information	Comment	Organism
physiological function	mutants lacking subunits cydA and cydAB are hypersusceptible to compounds targeting the mycobacterial bc1 menaquinol cytochrome c oxidoreductase and exhibit bioenergetic profiles indistinguishable from strains deficient in the ABC-type transporter, CydDC, predicted to be essential for cytochrome bd assembly	Mycobacterium tuberculosis

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Release 2023.1 (January 2023)