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Literature summary extracted from

  • Das, M.; Radhakrishnan, A.N.
    Substrate specificity of a highly active dipeptidase purified from monkey small intestine (1972), Biochem. J., 128, 463-465.
    View publication on PubMedView publication on EuropePMC

General Stability

EC Number General Stability Organism
3.4.13.18 extremely unstable, even in presence of DTT Platyrrhini
3.4.13.18 stabilized to only a limited extent in the presence of 50%-saturated (NH4)2SO4 or 12.5% v/v glycerol Platyrrhini

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.13.18 Co2+ slight inhibition Platyrrhini
3.4.13.18 DTT above 1 mM Platyrrhini
3.4.13.18 EDTA
-
 Platyrrhini
3.4.13.18 Mg2+ slight inhibition Platyrrhini
3.4.13.18 Mn2+ slight inhibition Platyrrhini
3.4.13.18 p-hydroxymercuribenzoate
-
 Platyrrhini

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.4.13.18 10.6
-
 Gly-L-Leu
-
 Platyrrhini
3.4.13.18 20
-
 Gly-L-Val
-
 Platyrrhini
3.4.13.18 21
-
 Gly-L-Ile
-
 Platyrrhini

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.4.13.18 Zn2+ 0.1 mM Zn2+ activates Platyrrhini

Organism

EC Number Organism UniProt Comment Textmining
3.4.13.18 Platyrrhini
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.4.13.18
-
 Platyrrhini

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.13.18 small intestine
-
 Platyrrhini
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.4.13.18 additional information
-
-
 Platyrrhini

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.13.18 Ala-Leu + H2O
-
 Platyrrhini Ala + Leu
-
 ?
3.4.13.18 Gly-Ile + H2O
-
 Platyrrhini Gly + Ile
-
 ?
3.4.13.18 Gly-Leu + H2O
-
 Platyrrhini Gly + Leu
-
 ?
3.4.13.18 Gly-Val + H2O
-
 Platyrrhini Gly + Val
-
 ?
3.4.13.18 Leu-Gly + H2O
-
 Platyrrhini Leu + Gly
-
 ?
3.4.13.18 additional information specificity overview Platyrrhini ?
-
 ?
3.4.13.18 additional information not: Gly-Gly Platyrrhini ?
-
 ?
3.4.13.18 additional information not: Leu-Leu Platyrrhini ?
-
 ?
3.4.13.18 additional information not: Ala-Leu Platyrrhini ?
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.4.13.18 7.8
-
 Gly-L-Leu, Gly-L-Val, Gly-L-Ile Platyrrhini