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Literature summary extracted from
- Characterisation and sequence of the Chryseobacterium (flavobacterium) meningosepticum carbapenemase: a new molecular class B beta-lactamase showing a broad substrate profile (1998), Biochem. J., 332, 145-152.
No PubMed abstract available
Cloned(Commentary)
| EC Number | Cloned (Comment) | Organism |
|---|---|---|
| 3.5.2.6 | - |
Elizabethkingia meningoseptica |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.5.2.6 | 1,10-phenanthroline | - |
Elizabethkingia meningoseptica |  |
| 3.5.2.6 | EDTA | - |
Elizabethkingia meningoseptica | |
| 3.5.2.6 | pyridine-2,6-dicarboxylic acid | - |
Elizabethkingia meningoseptica | |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 3.5.2.6 | 0.024 | - |
cefoxitin | - |
Elizabethkingia meningoseptica | |
| 3.5.2.6 | 0.029 | - |
cephaloridine | - |
Elizabethkingia meningoseptica | |
| 3.5.2.6 | 0.032 | - |
penicillin G | - |
Elizabethkingia meningoseptica | |
| 3.5.2.6 | 0.043 | - |
6-beta-iodopenicillanate | - |
Elizabethkingia meningoseptica | |
| 3.5.2.6 | 0.066 | - |
nitrocefin | - |
Elizabethkingia meningoseptica | |
| 3.5.2.6 | 0.18 | - |
cefotaxime | - |
Elizabethkingia meningoseptica | |
| 3.5.2.6 | 0.37 | - |
Imipenem | - |
Elizabethkingia meningoseptica | |
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.5.2.6 | Zn2+ | - |
Elizabethkingia meningoseptica | |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 3.5.2.6 | 26000 | - |
SDS-PAGE | Elizabethkingia meningoseptica |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.5.2.6 | Elizabethkingia meningoseptica | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 3.5.2.6 | - |
Elizabethkingia meningoseptica |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 3.5.2.6 | 110 | - |
- |
Elizabethkingia meningoseptica |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.5.2.6 | 6-beta-iodopenicillanate + H2O | - |
Elizabethkingia meningoseptica | (2R,4S)-2-[(R)-carboxy(iodo)methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylate | - |
? | |
| 3.5.2.6 | cefotaxime + H2O | - |
Elizabethkingia meningoseptica | (2R)-5-[(acetyloxy)methyl]-2-[(R)-[[(2E)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino](carboxy)methyl]-3,6-dihydro-2H-1,3-thiazine-4-carboxylic acid | - |
? | |
| 3.5.2.6 | cefoxitin + H2O | - |
Elizabethkingia meningoseptica | (2R)-5-[(carbamoyloxy)methyl]-2-[(S)-carboxy(methoxy)[(thiophen-2-ylacetyl)amino]methyl]-3,6-dihydro-2H-1,3-thiazine-4-carboxylic acid | - |
? | |
| 3.5.2.6 | cephaloridine + H2O | - |
Elizabethkingia meningoseptica | (2R)-2-[(R)-carboxy[(thiophen-2-ylacetyl)amino]methyl]-5-(pyridinium-1-ylmethyl)-3,6-dihydro-2H-1,3-thiazine-4-carboxylate | - |
? | |
| 3.5.2.6 | imipenem + H2O | - |
Elizabethkingia meningoseptica | (5R)-5-[(1S,2R)-1-carboxy-2-hydroxypropyl]-3-({2-[(iminomethyl)amino]ethyl}sulfanyl)-4,5-dihydro-1H-pyrrole-2-carboxylic acid | - |
? | |
| 3.5.2.6 | nitrocefin + H2O | - |
Elizabethkingia meningoseptica | (2R)-2-{(R)-carboxy[2-(thiophen-2-yl)acetamido]methyl}-5-[(E)-2-(2,4-dinitrophenyl)ethenyl]-3,6-dihydro-2H-1,3-thiazine-4-carboxylic acid | - |
? | |
| 3.5.2.6 | penicillin G + H2O | - |
Elizabethkingia meningoseptica | (2R,4S)-2-[(R)-carboxy[(phenylacetyl)amino]methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid | - |
? | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 3.5.2.6 | monomer | 1* 26000, SDS-PAGE | Elizabethkingia meningoseptica |
Turnover Number [1/s]
| EC Number | Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 3.5.2.6 | 6 | - |
cefoxitin | - |
Elizabethkingia meningoseptica | |
| 3.5.2.6 | 14 | - |
cephaloridine | - |
Elizabethkingia meningoseptica | |
| 3.5.2.6 | 17 | - |
nitrocefin | - |
Elizabethkingia meningoseptica | |
| 3.5.2.6 | 39 | - |
cefotaxime | - |
Elizabethkingia meningoseptica | |
| 3.5.2.6 | 280 | - |
penicillin G | - |
Elizabethkingia meningoseptica | |
| 3.5.2.6 | 300 | - |
6-beta-iodopenicillanate | - |
Elizabethkingia meningoseptica | |
| 3.5.2.6 | 350 | - |
Imipenem | - |
Elizabethkingia meningoseptica | |
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Release 2023.1 (January 2023)
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