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Literature summary extracted from

  • Petersen, M.; Alfermann, A.W.
    Two new enzymes of rosmarinic acid biosyntheses from cell cultures of Coleus blumei: hydroxyphenylpyruvate reductase and rosmarinic acid synthase (1988), Z. Naturforsch. C, 43, 501-504.
No PubMed abstract available

Activating Compound

EC Number Activating Compound Comment Organism Structure
1.1.1.237 ascorbic acid prevents oxidation of substrates Coleus scutellarioides
1.1.1.237 dithiothreitol
-
 Coleus scutellarioides

General Stability

EC Number General Stability Organism
1.1.1.237 sensitive to oxidation by light and oxygen Coleus scutellarioides

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.237 3-(4-hydroxyphenyl)lactate + NAD+ Coleus scutellarioides biosynthesis of rosmarinic acid 4-hydroxyphenylpyruvate + NADH + H+
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.237 Coleus scutellarioides
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.1.1.237 ammonium sulfate precipitation and Sephadex G25 column Coleus scutellarioides

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.237 3,4-dihydroxyphenylpyruvate + NADH + H+
-
 Coleus scutellarioides 3-(3,4-dihydroxyphenyl)lactate + NAD+
-
 ?
1.1.1.237 3-(4-hydroxyphenyl)lactate + NAD+ biosynthesis of rosmarinic acid Coleus scutellarioides 4-hydroxyphenylpyruvate + NADH + H+
-
 ?
1.1.1.237 4-hydroxyphenylpyruvate + NADH + H+
-
 Coleus scutellarioides 3-(4-hydroxyphenyl)lactate + NAD+
-
 ?

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.237 NAD+
-
 Coleus scutellarioides
1.1.1.237 NADP+ with lower activity than NAD+ Coleus scutellarioides