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Literature summary extracted from

  • Siegfried, C.M.
    Purification and properties of a factor from rat liver cytosol which stimulates vitamin K epoxide reductase (1983), Arch. Biochem. Biophys., 223, 129-139.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
1.17.4.4 Protein factor activation, two different protein factors from rat liver cytosol Rattus norvegicus

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.17.4.4 warfarin i.e. 3-(alpha-acetonylbenzyl)-4-hydroxycoumarin, inhibition decreased by DTT Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.17.4.4 microsome integral membrane protein Rattus norvegicus
-
-

Organism

EC Number Organism UniProt Comment Textmining
1.17.4.4 Rattus norvegicus
-
 Holtzman strain
-
1.17.4.4 Rattus norvegicus Holtzman
-
 Holtzman strain
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.17.4.4 liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.17.4.4 vitamin K 2,3-epoxide + dithiothreitol
-
 Rattus norvegicus vitamin K + oxidized dithiothreitol
-
 ?
1.17.4.4 vitamin K 2,3-epoxide + dithiothreitol
-
 Rattus norvegicus Holtzman vitamin K + oxidized dithiothreitol
-
 ?