Literature summary extracted from

Edwards, S.W.; Knox, W.E.
Homogentisate metabolism: The isomerization of meleylacetoacetate by an enzyme which requires glutathione (1956), J. Biol. Chem., 220, 79-91.

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
3.7.1.2	4-fumarylacetoacetate + H2O	Rattus norvegicus	-	acetoacetate + fumarate	-	?
3.7.1.2	4-fumarylacetoacetate + H2O	Bos taurus	-	acetoacetate + fumarate	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
3.7.1.2	Bos taurus	-	-	-
3.7.1.2	Rattus norvegicus	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
3.7.1.2	liver	-	Rattus norvegicus	-
3.7.1.2	liver	-	Bos taurus	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
3.7.1.2	4-fumarylacetoacetate + H2O	-	Rattus norvegicus	acetoacetate + fumarate	-	?
3.7.1.2	4-fumarylacetoacetate + H2O	-	Bos taurus	acetoacetate + fumarate	-	?

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Release 2023.1 (January 2023)