EC Number | Application | Comment | Organism |
---|---|---|---|
1.3.1.2 | medicine | rate limiting enzyme for detoxification of exogenous fluoropyrimidines, antitumor drug design | Sus scrofa |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.3.1.2 | Sus scrofa | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
1.3.1.2 | - |
Sus scrofa |
EC Number | Reaction | Comment | Organism | Reaction ID |
---|---|---|---|---|
1.3.1.2 | 5,6-dihydrouracil + NADP+ = uracil + NADPH + H+ | abstraction of pro-S hydrogen of NADPH and thus B-side stereospecific class dehydrogenase | Sus scrofa |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
1.3.1.2 | liver | - |
Sus scrofa | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.3.1.2 | uracil + NADPH | - |
Sus scrofa | 5,6-dihydrouracil + NADP+ | - |
? |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.3.1.2 | NADPH | strictly dependent on | Sus scrofa |