EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.14.14.19 | 3-(6-Chloro-3-methyl-2-indenyl)pyridine | competitive inhibitor | Sus scrofa | |
1.14.14.19 | 4-chloro-3,4-dihydro-2-(3-pyridyl)-1-(2H)-naphthalenone | competitive inhibitor | Sus scrofa | |
1.14.14.19 | CO | - |
Sus scrofa |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.14.14.19 | progesterone + [reduced NADPH-hemoprotein reductase] + O2 | Sus scrofa | - |
17alpha-hydroxyprogesterone + [oxidized NADPH-hemoprotein reductase] + H2O | product eliminates at C20,21 acetate to yield androstenedione | ? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.14.14.19 | Sus scrofa | - |
- |
- |
EC Number | Posttranslational Modification | Comment | Organism |
---|---|---|---|
1.14.14.19 | glycoprotein | three glucosamine residues per molecule | Sus scrofa |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
1.14.14.19 | testis | neonatal | Sus scrofa | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.14.14.19 | progesterone + [reduced NADPH-hemoprotein reductase] + O2 | - |
Sus scrofa | 17alpha-hydroxyprogesterone + [oxidized NADPH-hemoprotein reductase] + H2O | product eliminates at C20,21 acetate to yield androstenedione | ? |
EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|---|
1.14.14.19 | 37 | - |
- |
Sus scrofa |
EC Number | Temperature Minimum [°C] | Temperature Maximum [°C] | Comment | Organism |
---|---|---|---|---|
1.14.14.19 | 30 | 44 | hydroxylase and lyase activity decrease proportionally | Sus scrofa |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
1.14.14.19 | 7.3 | - |
- |
Sus scrofa |
EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|---|
1.14.14.19 | 0.00004 | - |
3-(6-Chloro-3-methyl-2-indenyl)pyridine | - |
Sus scrofa | |
1.14.14.19 | 0.0003 | - |
4-chloro-3,4-dihydro-2-(3-pyridyl)-1-(2H)-naphthalenone | - |
Sus scrofa |