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Literature summary extracted from

  • Paulin, L.; Poesoe, H.
    Ornithine decarboxylase activity from an extremely thermophilic bacterium, Clostridium thermohydrosulfuricum (1983), Biochim. Biophys. Acta, 742, 197-205.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
4.1.1.17 3'-O-Methyl-GTP stimulates Thermoanaerobacter thermohydrosulfuricus
4.1.1.17 7-methyl-GTP stimulates Thermoanaerobacter thermohydrosulfuricus
4.1.1.17 alpha,beta-methylene-GTP stimulates Thermoanaerobacter thermohydrosulfuricus
4.1.1.17 beta,gamma-methylene-GTP stimulates Thermoanaerobacter thermohydrosulfuricus
4.1.1.17 GTP stimulates Thermoanaerobacter thermohydrosulfuricus
4.1.1.17 GTP-gamma-S stimulates Thermoanaerobacter thermohydrosulfuricus
4.1.1.17 Guanosine 5'-pentaphosphate stimulates Thermoanaerobacter thermohydrosulfuricus
4.1.1.17 guanosine 5'-tetraphosphate stimulates Thermoanaerobacter thermohydrosulfuricus
4.1.1.17 ITP stimulates Thermoanaerobacter thermohydrosulfuricus

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.1.1.17 alpha-DL-difluoromethylornithine irreversibel Thermoanaerobacter thermohydrosulfuricus
4.1.1.17 putrescine no inhibition Thermoanaerobacter thermohydrosulfuricus
4.1.1.17 spermidine no inhibition Thermoanaerobacter thermohydrosulfuricus

Organism

EC Number Organism UniProt Comment Textmining
4.1.1.17 Thermoanaerobacter thermohydrosulfuricus
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.1.1.17 L-Orn
-
 Thermoanaerobacter thermohydrosulfuricus Putrescine + CO2
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
4.1.1.17 55
-
-
 Thermoanaerobacter thermohydrosulfuricus

Temperature Range [°C]

EC Number Temperature Minimum [°C] Temperature Maximum [°C] Comment Organism
4.1.1.17 35 65 35°C: about 60% of maximal activity, 65°C: about 45% of maximal activity Thermoanaerobacter thermohydrosulfuricus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
4.1.1.17 7.5
-
-
 Thermoanaerobacter thermohydrosulfuricus

pH Range

EC Number pH Minimum pH Maximum Comment Organism
4.1.1.17 6.5 9 pH 6.5: about 60% of maximal activity, pH 9.0: about 45% of maximal activity Thermoanaerobacter thermohydrosulfuricus

Cofactor

EC Number Cofactor Comment Organism Structure
4.1.1.17 dGTP stimulates Thermoanaerobacter thermohydrosulfuricus
4.1.1.17 GDP stimulates Thermoanaerobacter thermohydrosulfuricus
4.1.1.17 GMP stimulates Thermoanaerobacter thermohydrosulfuricus
4.1.1.17 pyridoxal 5'-phosphate required Thermoanaerobacter thermohydrosulfuricus