EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
1.17.4.2 | dATP | specific activator for CTP reduction | Lactobacillus leichmannii | |
1.17.4.2 | dCTP | specific activator for UTP reduction | Lactobacillus leichmannii | |
1.17.4.2 | dGTP | specific activator for ATP reduction | Lactobacillus leichmannii | |
1.17.4.2 | dTTP | specific activator for ITP reduction | Lactobacillus leichmannii |
EC Number | General Stability | Organism |
---|---|---|
1.17.4.2 | fairly stable under conditions of storage, losing only about 23% of its activity in 15 months | Lactobacillus leichmannii |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.17.4.2 | 2'-deoxyadenosylcobalamin | - |
Lactobacillus leichmannii | |
1.17.4.2 | 3-isoadenosylcobalamin | - |
Lactobacillus leichmannii | |
1.17.4.2 | adenosylcobalamin | - |
Lactobacillus leichmannii | |
1.17.4.2 | isopropylideneadenosylcobalamin | - |
Lactobacillus leichmannii | |
1.17.4.2 | nebularylcobalamin | - |
Lactobacillus leichmannii | |
1.17.4.2 | tubercidylcobalamin | - |
Lactobacillus leichmannii |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
1.17.4.2 | 0.0003 | - |
adenosylcobalamin | presence of 1.0 mM CTP and 1 mM dATP | Lactobacillus leichmannii | |
1.17.4.2 | 0.00045 | - |
adenosylcobalamin | presence of 0.1 mM CTP and 1 mM dATP | Lactobacillus leichmannii | |
1.17.4.2 | 0.0055 | - |
adenosylcobalamin | presence of 2 mM CTP without activator | Lactobacillus leichmannii | |
1.17.4.2 | 0.13 | - |
CTP | presence of 1 mM dATP | Lactobacillus leichmannii | |
1.17.4.2 | 0.22 | - |
ATP | presence of 1 mM dGTP | Lactobacillus leichmannii |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
1.17.4.2 | Cs+ | activating effect | Lactobacillus leichmannii | |
1.17.4.2 | K+ | activating effect | Lactobacillus leichmannii | |
1.17.4.2 | Li+ | activating effect | Lactobacillus leichmannii | |
1.17.4.2 | Na+ | activating effect | Lactobacillus leichmannii | |
1.17.4.2 | NH4+ | activating effect | Lactobacillus leichmannii | |
1.17.4.2 | Rb+ | activating effect | Lactobacillus leichmannii |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
1.17.4.2 | 76000 | - |
- |
Lactobacillus leichmannii |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.17.4.2 | ribonucleoside triphosphate + reduced thioredoxin + H2O | Pseudomonas sp. | - |
2'-deoxyribonucleoside triphosphate + oxidized thioredoxin + H2O | - |
r | |
1.17.4.2 | ribonucleoside triphosphate + reduced thioredoxin + H2O | Corynebacterium sp. | - |
2'-deoxyribonucleoside triphosphate + oxidized thioredoxin + H2O | - |
r | |
1.17.4.2 | ribonucleoside triphosphate + reduced thioredoxin + H2O | Clostridium sp. | - |
2'-deoxyribonucleoside triphosphate + oxidized thioredoxin + H2O | - |
r | |
1.17.4.2 | ribonucleoside triphosphate + reduced thioredoxin + H2O | Rhizobium sp. | - |
2'-deoxyribonucleoside triphosphate + oxidized thioredoxin + H2O | - |
r | |
1.17.4.2 | ribonucleoside triphosphate + reduced thioredoxin + H2O | Euglena sp. | - |
2'-deoxyribonucleoside triphosphate + oxidized thioredoxin + H2O | - |
r | |
1.17.4.2 | ribonucleoside triphosphate + reduced thioredoxin + H2O | Lactobacillus leichmannii | - |
2'-deoxyribonucleoside triphosphate + oxidized thioredoxin + H2O | - |
r | |
1.17.4.2 | ribonucleoside triphosphate + reduced thioredoxin + H2O | Astasia sp. | - |
2'-deoxyribonucleoside triphosphate + oxidized thioredoxin + H2O | - |
r |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.17.4.2 | Astasia sp. | - |
euglenoid flagellate | - |
1.17.4.2 | Clostridium sp. | - |
- |
- |
1.17.4.2 | Corynebacterium sp. | - |
- |
- |
1.17.4.2 | Euglena sp. | - |
euglenoid flagellate | - |
1.17.4.2 | Lactobacillus leichmannii | - |
strain ATCC 4797 | - |
1.17.4.2 | Pseudomonas sp. | - |
- |
- |
1.17.4.2 | Rhizobium sp. | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
1.17.4.2 | - |
Lactobacillus leichmannii |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
1.17.4.2 | 2.82 | - |
- |
Lactobacillus leichmannii |
EC Number | Storage Stability | Organism |
---|---|---|
1.17.4.2 | -100°C, may be stored as frozen paste for at least 3 months without significant loss of activity | Lactobacillus leichmannii |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.17.4.2 | ATP + reduced thioredoxin | - |
Lactobacillus leichmannii | dATP + oxidized thioredoxin + H2O | - |
? | |
1.17.4.2 | ribonucleoside triphosphate + dihydrolipoate | - |
Lactobacillus leichmannii | 2'-deoxyribonucleoside triphosphate + lipoate + H2O | - |
? | |
1.17.4.2 | ribonucleoside triphosphate + dithioerythritol | - |
Lactobacillus leichmannii | 2'-deoxyribonucleoside triphosphate + ? + H2O | - |
? | |
1.17.4.2 | ribonucleoside triphosphate + dithiothreitol | - |
Lactobacillus leichmannii | 2'-deoxyribonucleoside triphosphate + ? + H2O | - |
? | |
1.17.4.2 | ribonucleoside triphosphate + reduced thioredoxin | - |
Pseudomonas sp. | 2'-deoxyribonucleoside triphosphate + oxidized thioredoxin + H2O | - |
r | |
1.17.4.2 | ribonucleoside triphosphate + reduced thioredoxin | - |
Corynebacterium sp. | 2'-deoxyribonucleoside triphosphate + oxidized thioredoxin + H2O | - |
r | |
1.17.4.2 | ribonucleoside triphosphate + reduced thioredoxin | - |
Clostridium sp. | 2'-deoxyribonucleoside triphosphate + oxidized thioredoxin + H2O | - |
r | |
1.17.4.2 | ribonucleoside triphosphate + reduced thioredoxin | - |
Rhizobium sp. | 2'-deoxyribonucleoside triphosphate + oxidized thioredoxin + H2O | - |
r | |
1.17.4.2 | ribonucleoside triphosphate + reduced thioredoxin | - |
Euglena sp. | 2'-deoxyribonucleoside triphosphate + oxidized thioredoxin + H2O | - |
r | |
1.17.4.2 | ribonucleoside triphosphate + reduced thioredoxin | - |
Lactobacillus leichmannii | 2'-deoxyribonucleoside triphosphate + oxidized thioredoxin + H2O | - |
r | |
1.17.4.2 | ribonucleoside triphosphate + reduced thioredoxin | - |
Astasia sp. | 2'-deoxyribonucleoside triphosphate + oxidized thioredoxin + H2O | - |
r | |
1.17.4.2 | ribonucleoside triphosphate + reduced thioredoxin | - |
Pseudomonas sp. | deoxyribonucleoside triphosphate + oxidized thioredoxin + H2O | - |
? | |
1.17.4.2 | ribonucleoside triphosphate + reduced thioredoxin | - |
Corynebacterium sp. | deoxyribonucleoside triphosphate + oxidized thioredoxin + H2O | - |
? | |
1.17.4.2 | ribonucleoside triphosphate + reduced thioredoxin | - |
Clostridium sp. | deoxyribonucleoside triphosphate + oxidized thioredoxin + H2O | - |
? | |
1.17.4.2 | ribonucleoside triphosphate + reduced thioredoxin | - |
Rhizobium sp. | deoxyribonucleoside triphosphate + oxidized thioredoxin + H2O | - |
? | |
1.17.4.2 | ribonucleoside triphosphate + reduced thioredoxin | - |
Euglena sp. | deoxyribonucleoside triphosphate + oxidized thioredoxin + H2O | - |
? | |
1.17.4.2 | ribonucleoside triphosphate + reduced thioredoxin | - |
Lactobacillus leichmannii | deoxyribonucleoside triphosphate + oxidized thioredoxin + H2O | - |
? | |
1.17.4.2 | ribonucleoside triphosphate + reduced thioredoxin | - |
Astasia sp. | deoxyribonucleoside triphosphate + oxidized thioredoxin + H2O | - |
? | |
1.17.4.2 | ribonucleoside triphosphate + reduced thioredoxin + H2O | - |
Pseudomonas sp. | 2'-deoxyribonucleoside triphosphate + oxidized thioredoxin + H2O | - |
r | |
1.17.4.2 | ribonucleoside triphosphate + reduced thioredoxin + H2O | - |
Corynebacterium sp. | 2'-deoxyribonucleoside triphosphate + oxidized thioredoxin + H2O | - |
r | |
1.17.4.2 | ribonucleoside triphosphate + reduced thioredoxin + H2O | - |
Clostridium sp. | 2'-deoxyribonucleoside triphosphate + oxidized thioredoxin + H2O | - |
r | |
1.17.4.2 | ribonucleoside triphosphate + reduced thioredoxin + H2O | - |
Rhizobium sp. | 2'-deoxyribonucleoside triphosphate + oxidized thioredoxin + H2O | - |
r | |
1.17.4.2 | ribonucleoside triphosphate + reduced thioredoxin + H2O | - |
Euglena sp. | 2'-deoxyribonucleoside triphosphate + oxidized thioredoxin + H2O | - |
r | |
1.17.4.2 | ribonucleoside triphosphate + reduced thioredoxin + H2O | - |
Lactobacillus leichmannii | 2'-deoxyribonucleoside triphosphate + oxidized thioredoxin + H2O | - |
r | |
1.17.4.2 | ribonucleoside triphosphate + reduced thioredoxin + H2O | - |
Astasia sp. | 2'-deoxyribonucleoside triphosphate + oxidized thioredoxin + H2O | - |
r |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
1.17.4.2 | monomer | - |
Lactobacillus leichmannii |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.17.4.2 | Coalpha-(aden-9-yl)-Cobeta-adenosylcobamide | - |
Lactobacillus leichmannii | |
1.17.4.2 | Coalpha-(benzimidazolyl)-Cobeta-adenosylcobamide | - |
Lactobacillus leichmannii | |
1.17.4.2 | coenzyme B12 | adenosylcobalamin | Pseudomonas sp. | |
1.17.4.2 | coenzyme B12 | adenosylcobalamin | Corynebacterium sp. | |
1.17.4.2 | coenzyme B12 | adenosylcobalamin | Clostridium sp. | |
1.17.4.2 | coenzyme B12 | adenosylcobalamin | Rhizobium sp. | |
1.17.4.2 | coenzyme B12 | adenosylcobalamin | Euglena sp. | |
1.17.4.2 | coenzyme B12 | adenosylcobalamin | Lactobacillus leichmannii | |
1.17.4.2 | coenzyme B12 | adenosylcobalamin | Astasia sp. |