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Literature summary extracted from

  • Imaizumi, K.; Tsuda, M.; Wanaka, A.; Tohyama, M.; Takagi, T.
    Differential expression of sgk mRNA, a member of the Ser/Thr protein kinase gene family, in rat brain after CNS injury (1994), Brain Res. Mol. Brain Res., 26, 189-196.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.11.1 additional information Rattus norvegicus the enzyme is transcriptionally regulated by serum and glucocorticoids in mammary epithelial cells, hormone-regulated protein kinase gene with a functionally defined p53 promoter recognition element ?
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2.7.11.1 additional information Rattus norvegicus induction of sgk gene may be associated with a series of axonal regenerations after brain injury, and in addition, the sgk gene may also play important roles in the development of particular groups of neurons in the postnatal brain ?
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Organism

EC Number Organism UniProt Comment Textmining
2.7.11.1 Rattus norvegicus Q06226
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Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.11.1 brain the cells which strongly express the sgk gene are in the deep layers of the cortex and in the corpus callosum. It is likely that the sgk transcript is expressed by oligodendrocytes after brain injury. Neurons in layers I and II of the cortex, lateroposterior and laterodorsal thalamic nucleus, and ventral posterolateral and posteromedial thalamic nucleus strongly express sgk mRNA at postnatal day 1 and day 7, but these neurons show no expression in fetal or adult brain. Induction of sgk gene may be associated with a series of axonal regenerations after brain injury, and in addition, the sgk gene may also play important roles in the development of particular groups of neurons in the postnatal brain Rattus norvegicus
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.11.1 additional information the enzyme is transcriptionally regulated by serum and glucocorticoids in mammary epithelial cells, hormone-regulated protein kinase gene with a functionally defined p53 promoter recognition element Rattus norvegicus ?
-
 ?
2.7.11.1 additional information induction of sgk gene may be associated with a series of axonal regenerations after brain injury, and in addition, the sgk gene may also play important roles in the development of particular groups of neurons in the postnatal brain Rattus norvegicus ?
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 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.11.1 serine/threonine-protein kinase Sgk
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 Rattus norvegicus