Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Webster, M.K.; Goya, L.; Ge, Y.; Maiyar, A.C.; Firestone, G.L.
    Characterization of sgk, a novel member of the serine/threonine protein kinase gene family which is transcriptionally induced by glucocorticoids and serum (1993), Mol. Cell. Biol., 13, 2031-2040.
    View publication on PubMedView publication on EuropePMC

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.7.11.1 49000
-
 x * 49000 Rattus norvegicus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.11.1 additional information Rattus norvegicus the enzyme is transcriptionally regulated by serum and glucocorticoids in mammary epithelial cells, hormone-regulated protein kinase gene with a functionally defined p53 promoter recognition element ?
-
 ?
2.7.11.1 additional information Rattus norvegicus the enzyme is highly regulated at the transcriptional level by glucocorticoid hormones ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.11.1 Rattus norvegicus Q06226
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.11.1 cell culture Con8.hd6 rat mammary tumor cell line Rattus norvegicus
-
2.7.11.1 lung high activity Rattus norvegicus
-
2.7.11.1 ovary high activity Rattus norvegicus
-
2.7.11.1 thymus high activity Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.11.1 additional information the enzyme is transcriptionally regulated by serum and glucocorticoids in mammary epithelial cells, hormone-regulated protein kinase gene with a functionally defined p53 promoter recognition element Rattus norvegicus ?
-
 ?
2.7.11.1 additional information the enzyme is highly regulated at the transcriptional level by glucocorticoid hormones Rattus norvegicus ?
-
 ?

Subunits

EC Number Subunits Comment Organism
2.7.11.1 ? x * 49000 Rattus norvegicus

Synonyms

EC Number Synonyms Comment Organism
2.7.11.1 serine/threonine-protein kinase Sgk
-
 Rattus norvegicus