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Literature summary extracted from
- Ether-cleaving enzyme and diol dehydratase involved in anaerobic polyethylene glycol degradation by a new Acetobacterium sp (1991), Biodegradation, 2, 71-79.
Application
| EC Number | Application | Comment | Organism |
|---|---|---|---|
| 4.2.1.28 | degradation | possible use in anaerobic polyethylene glycol degradation | Acetobacterium sp. |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 4.2.1.28 | adenosylcobalamin | analogues | Acetobacterium sp. |  |
| 4.2.1.28 | glycerol | complete inhibition at 50-100 mM | Acetobacterium sp. | |
| 4.2.1.28 | K+ | 16% inhibition at 40 mM | Acetobacterium sp. | |
| 4.2.1.28 | Mg2+ | 69% inhibition at 40 mM | Acetobacterium sp. | |
| 4.2.1.28 | Na+ | 41% inhibition at 40 mM | Acetobacterium sp. | |
| 4.2.1.28 | Rb+ | 35% inhibition at 40 mM | Acetobacterium sp. | |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 4.2.1.28 | cell membrane | 35% of activity | Acetobacterium sp. | - |
- |
| 4.2.1.28 | cytoplasm | 65% of activity | Acetobacterium sp. | 5737 | - |
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 4.2.1.28 | NH4+ | 6% stimulation at 40 mM | Acetobacterium sp. | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 4.2.1.28 | Acetobacterium sp. | - |
- |
- |
Oxidation Stability
| EC Number | Oxidation Stability | Organism |
|---|---|---|
| 4.2.1.28 | 50% loss of activity after 4 h under air | Acetobacterium sp. |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.2.1.28 | 1,2-propanediol | - |
Acetobacterium sp. | propanal | - |
? | |
| 4.2.1.28 | ethylene glycol | - |
Acetobacterium sp. | acetaldehyde | - |
? | |
Temperature Optimum [°C]
| EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|---|
| 4.2.1.28 | 25 | - |
enzyme assay at | Acetobacterium sp. |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 4.2.1.28 | 8 | - |
enzyme assay at | Acetobacterium sp. |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 4.2.1.28 | cobamide | - |
Acetobacterium sp. | |
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Release 2023.1 (January 2023)
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