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Literature summary extracted from

  • Tunnicliff, G.; Ngo, T.T.; Rojo-Ortega, J.M.; Barbeau, A.
    The inhibition by substrate analogues of gamma-aminobutyrate aminotransferase from mitochondria of different subcellular fractions of rat brain (1977), Can. J. Biochem., 55, 479-484.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.6.1.19 2,4-diaminobutanoate kinetics Rattus norvegicus
2.6.1.19 Aminooxyacetate kinetics Rattus norvegicus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.6.1.19 6.5
-
 4-aminobutanoate mitochondrial enzyme Rattus norvegicus
2.6.1.19 6.5
-
 4-aminobutanoate pH 8.0 Rattus norvegicus
2.6.1.19 53
-
 4-aminobutanoate synaptosomal enzyme, pH 8.0 Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.6.1.19 mitochondrion
-
 Rattus norvegicus 5739
-
2.6.1.19 synaptosome
-
 Rattus norvegicus
-
-

Organism

EC Number Organism UniProt Comment Textmining
2.6.1.19 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.6.1.19 brain
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.6.1.19 4-aminobutanoate + 2-oxoglutarate
-
 Rattus norvegicus 4-oxobutanoate + L-glutamate
-
 r
2.6.1.19 beta-alanine + 2-oxoglutarate
-
 Rattus norvegicus malonic semialdehyde + L-glutamate
-
 r

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
2.6.1.19 0.008
-
 2,4-diaminobutanoate synaptosomal enzyme, pH 8.0 Rattus norvegicus
2.6.1.19 0.013
-
 2,4-diaminobutanoate cytoplasmic enzyme, pH 8.0 Rattus norvegicus