Literature summary extracted from

MacRae, I.J.; Segel, I.H.; Fisher, A.J.
Allosteric inhibition via R-state destabilization in ATP sulfurylase from Penicillium chrysogenum (2002), Nat. Struct. Biol., 9, 945-949.

Crystallization (Commentary)

EC Number	Crystallization (Comment)	Organism
2.7.7.4	recombinant enzyme expressed in Escherichia coli, crystals are grown at 22°C by vapor diffusion in hanging drops, crystal structure of the enzyme bound to the allosteric inhibitor 3'-phosphoadenosine-5'-phosphosulfate determined at 2.6 A resolution	Penicillium chrysogenum

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
2.7.7.4	3'-phosphoadenosine-5'-phosphate	allosteric	Penicillium chrysogenum

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.7.7.4	Penicillium chrysogenum	Q12650	-	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.7.7.4	ATP + sulfate	-	Penicillium chrysogenum	diphosphate + adenylylsulfate	-	r

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)