EC Number | Crystallization (Comment) | Organism |
---|---|---|
2.7.1.156 | X-ray crystal structure determined by molecular replacement to 2.2 A resolution, crystals grown by the batch method, cocrystallized with GTP and diphosphate, crystals belong to space group P2(1)2(1)2(1) with unit cell dimensions a : 58.4 A, b : 87.8 A, and c : 101.6 A | Salmonella enterica subsp. enterica serovar Typhimurium |
2.7.7.62 | X-ray crystal structure determined by molecular replacement to 2.2 A resolution, crystals grown by the batch method, cocrystallized with GTP and diphosphate, crystals belong to space group P2(1)2(1)2(1) with unit cell dimensions a : 58.4 A, b : 87.8 A, and c : 101.6 A | Salmonella enterica subsp. enterica serovar Typhimurium |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.7.1.156 | diphosphate | - |
Salmonella enterica subsp. enterica serovar Typhimurium |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
2.7.1.156 | 19000 | - |
3 * 19000, homotrimer | Salmonella enterica subsp. enterica serovar Typhimurium |
2.7.7.62 | 19000 | - |
3 * 19000, homotrimer | Salmonella enterica subsp. enterica serovar Typhimurium |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.7.62 | GTP + adenosylcobinamide phosphate | Salmonella enterica subsp. enterica serovar Typhimurium | biosynthesis of cobalamin, enzyme catalyzes the phosphorylation of the 1-amino-O-2-propanol side chain of the adenosylcobinamide ring | diphosphate + adenosylcobinamide-GDP | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.7.1.156 | Salmonella enterica subsp. enterica serovar Typhimurium | - |
- |
- |
2.7.7.62 | Salmonella enterica subsp. enterica serovar Typhimurium | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
2.7.1.156 | - |
Salmonella enterica subsp. enterica serovar Typhimurium |
2.7.7.62 | - |
Salmonella enterica subsp. enterica serovar Typhimurium |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.7.62 | GTP + adenosylcobinamide phosphate | - |
Salmonella enterica subsp. enterica serovar Typhimurium | diphosphate + adenosylcobinamide-GDP | - |
? | |
2.7.7.62 | GTP + adenosylcobinamide phosphate | biosynthesis of cobalamin, enzyme catalyzes the phosphorylation of the 1-amino-O-2-propanol side chain of the adenosylcobinamide ring | Salmonella enterica subsp. enterica serovar Typhimurium | diphosphate + adenosylcobinamide-GDP | - |
? | |
2.7.7.62 | additional information | CobU is a bifunctional enzyme that has both kinase EC 2.7.1.156 and guanyltransferase EC 2.7.7.62 activities | Salmonella enterica subsp. enterica serovar Typhimurium | ? | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
2.7.1.156 | trimer | 3 * 19000, homotrimer | Salmonella enterica subsp. enterica serovar Typhimurium |
2.7.7.62 | trimer | 3 * 19000, homotrimer | Salmonella enterica subsp. enterica serovar Typhimurium |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.7.1.156 | adenosylcobinamide kinase | - |
Salmonella enterica subsp. enterica serovar Typhimurium |
2.7.1.156 | CobU | - |
Salmonella enterica subsp. enterica serovar Typhimurium |
2.7.7.62 | adenosylcobinamide phosphate guanyltransferase | - |
Salmonella enterica subsp. enterica serovar Typhimurium |
2.7.7.62 | CobU | - |
Salmonella enterica subsp. enterica serovar Typhimurium |