Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Vargas, F.; Frerot, O.; Tuong, M.D.T.; Schwartz, J.C.
    Characterization of a tyrosine sulfotransferase in rat brain using cholecystokinin derivatives as acceptors (1985), Biochemistry, 24, 5938-5943.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.8.2.9 2,6-Dichloro-4-nitrophenol
-
Rattus norvegicus
2.8.2.9 4-chloromercuribenzoate
-
Rattus norvegicus
2.8.2.9 adenosine 5'-triphosphate
-
Rattus norvegicus
2.8.2.9 CaCl2
-
Rattus norvegicus
2.8.2.9 CoCl2
-
Rattus norvegicus
2.8.2.9 CuCl2
-
Rattus norvegicus
2.8.2.9 EDTA
-
Rattus norvegicus
2.8.2.9 FeCl3
-
Rattus norvegicus
2.8.2.9 MgCl2
-
Rattus norvegicus
2.8.2.9 Triton X-100
-
Rattus norvegicus
2.8.2.9 V2O5
-
Rattus norvegicus
2.8.2.9 ZnCl2
-
Rattus norvegicus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.8.2.9 additional information
-
additional information
-
Rattus norvegicus
2.8.2.9 0.00012
-
3'-phosphoadenylylsulfate pH 7.4, 37°C Rattus norvegicus
2.8.2.9 0.14
-
t-butyloxycarbonyl-cholecystokinin-octapeptide pH 7.4, 37°C Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.8.2.9 microsome
-
Rattus norvegicus
-
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.8.2.9 MnCl2 activates at 0.2 mM Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
2.8.2.9 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.8.2.9 brain cerebral cortex Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.8.2.9 3'-phosphoadenylylsulfate + Asp-Arg-Asp-Tyr-Met-Gly
-
Rattus norvegicus adenosine 3',5'-bisphosphate + ?
-
?
2.8.2.9 3'-phosphoadenylylsulfate + caerulein nonsulfated Rattus norvegicus adenosine 3',5'-bisphosphate + ?
-
?
2.8.2.9 3'-phosphoadenylylsulfate + cholecystokinin nonsulfated Rattus norvegicus adenosine 3',5'-bisphosphate + ?
-
?
2.8.2.9 3'-phosphoadenylylsulfate + tert-butoxycarbonyl-Asp-Arg-Asp-Tyr-Met-Gly
-
Rattus norvegicus adenosine 3',5'-bisphosphate + ?
-
?
2.8.2.9 3'-phosphoadenylylsulfate + tert-butoxycarbonyl-Asp-Tyr
-
Rattus norvegicus adenosine 3',5'-bisphosphate + tert-butoxycarbonyl-Asp-Tyr-O4-sulfate
-
?
2.8.2.9 3'-phosphoadenylylsulfate + tert-butoxycarbonyl-Asp-Tyr-Met
-
Rattus norvegicus adenosine 3',5'-bisphosphate + tert-butoxycarbonyl-Asp-Tyr-(O4-sulfate)-Met
-
?
2.8.2.9 3'-phosphoadenylylsulfate + tert-butoxycarbonyl-Asp-Tyr-Met-Gly
-
Rattus norvegicus adenosine 3',5'-bisphosphate + tert-butoxycarbonyl-Asp-Tyr-(O4-sulfate)-Met-Gly
-
?
2.8.2.9 3'-phosphoadenylylsulfate + tert-butoxycarbonyl-Asp-Tyr-Met-Gly-Trp
-
Rattus norvegicus adenosine 3',5'-bisphosphate + tert-butoxycarbonyl-Asp-Tyr-(O4-sulfate)-Met-Gly-Trp
-
?
2.8.2.9 3'-phosphoadenylylsulfate + tert-butoxycarbonyl-Asp-Tyr-Met-Gly-Trp-Met
-
Rattus norvegicus adenosine 3',5'-bisphosphate + tert-butoxycarbonyl-Asp-Tyr-(O4-sulfate)-Met-Gly-Trp-Met
-
?
2.8.2.9 3'-phosphoadenylylsulfate + tert-butoxycarbonyl-Asp-Tyr-Met-Gly-Trp-Met-Asp-Phe-NH2 i.e. Boc-CCK-8 ns Rattus norvegicus adenosine 3',5'-bisphosphate + tert-butoxycarbonyl-Asp-Tyr-(O4-sulfate)-Met-Gly-Trp-Met-Asp-Phe-NH2
-
?
2.8.2.9 3'-phosphoadenylylsulfate + tert-butoxycarbonylcholecystokinin-octapeptide
-
Rattus norvegicus adenosine 3',5'-bisphosphate + ?
-
?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.8.2.9 5.8
-
-
Rattus norvegicus

pH Range

EC Number pH Minimum pH Maximum Comment Organism
2.8.2.9 additional information
-
-
Rattus norvegicus

pH Stability

EC Number pH Stability pH Stability Maximum Comment Organism
2.8.2.9 7
-
activity strongly decreases above pH 7 Rattus norvegicus