EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
2.8.2.1 | ferulic acid | activation of M-PST | Homo sapiens | |
2.8.2.1 | gallic acid | activation of P-PST and M-PST | Homo sapiens | |
2.8.2.1 | gentisic acid | activation of P-PST and M-PST | Homo sapiens | |
2.8.2.1 | m-coumaric acid | activation of P-PST | Homo sapiens | |
2.8.2.1 | o-coumaric acid | activation of P-PST | Homo sapiens | |
2.8.2.1 | p-coumaric acid | activation of P-PST | Homo sapiens | |
2.8.2.1 | p-hydroxybenzoic acid | activation of P-PST and M-PST | Homo sapiens |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.8.2.1 | caffeic acid | inhibition of P-PST and M-PST | Homo sapiens | |
2.8.2.1 | chlorogenic acid | inhibition of P-PST and M-PST | Homo sapiens | |
2.8.2.1 | protocatechuic acid | inhibition of P-PST and M-PST | Homo sapiens | |
2.8.2.1 | Sinapic acid | inhibition of P-PST and M-PST | Homo sapiens | |
2.8.2.1 | syringic acid | inhibition of P-PST and M-PST | Homo sapiens | |
2.8.2.1 | vanillic acid | inhibition of P-PST and M-PST | Homo sapiens |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.8.2.1 | 3'-phosphoadenylylsulfate + a phenol | Homo sapiens | sulfate conjugation of phenolic biogenic amines, important in the biotransformation of many neurotransmitters, hormones, drugs, and xenobiotic compounds | adenosine 3',5'-bisphosphate + an aryl sulfate | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.8.2.1 | Homo sapiens | - |
2 forms: simple phenol sulfating P-PST, monoamine sulfating M-PST | - |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.8.2.1 | platelet | M-PST | Homo sapiens | - |
2.8.2.1 | platelet | P-PST | Homo sapiens | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.8.2.1 | 3'-phosphoadenylyl sulfate + a phenol | - |
Homo sapiens | adenosine 3',5'-bisphosphate + an aryl sulfate | - |
? | |
2.8.2.1 | 3'-phosphoadenylylsulfate + 4-nitrophenol | P-PST | Homo sapiens | adenosine 3',5'-bisphosphate + 4-nitrophenyl sulfate | - |
? | |
2.8.2.1 | 3'-phosphoadenylylsulfate + a phenol | sulfate conjugation of phenolic biogenic amines, important in the biotransformation of many neurotransmitters, hormones, drugs, and xenobiotic compounds | Homo sapiens | adenosine 3',5'-bisphosphate + an aryl sulfate | - |
? | |
2.8.2.1 | 3'-phosphoadenylylsulfate + dopamine | M-PST | Homo sapiens | adenosine 3',5'-bisphosphate + ? | - |
? |
EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|---|
2.8.2.1 | 37 | - |
assay at | Homo sapiens |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
2.8.2.1 | 7 | - |
assay at | Homo sapiens |