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Literature summary extracted from

  • Nakajima, K.; Sonoda, H.; Mizoguchi, T.; Aoki, J.; Arai, H.; Nagahama, M.; Tagaya, M.; Tani, K.
    A novel phospholipase A1 with sequence homology to a mammalian Sec23p-interacting protein, p125 (2002), J. Biol. Chem., 277, 11329-11335.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.1.1.32 cloning of cDNA, transient expression in 293 T cells Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.1.1.32 cytosol predominantly Homo sapiens 5829
-
3.1.1.32 microsome
-
 Homo sapiens
-
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.1.1.32 90000
-
 x * 90000, SDS-PAGE, immunoblot Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.1.32 phosphatidic acid + H2O Homo sapiens
-
 2-acyl-lysophosphatidic acid + a carboxylate
-
 ?
3.1.1.32 phosphatidylcholine + H2O Homo sapiens
-
 2-acylglycerophosphocholine + a carboxylate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.1.32 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.1.32 brain northern analysis Homo sapiens
-
3.1.1.32 heart northern analysis Homo sapiens
-
3.1.1.32 kidney northern analysis Homo sapiens
-
3.1.1.32 liver northern analysis Homo sapiens
-
3.1.1.32 lung northern analysis Homo sapiens
-
3.1.1.32 pancreas northern analysis Homo sapiens
-
3.1.1.32 placenta northern analysis Homo sapiens
-
3.1.1.32 skeletal muscle northern analysis Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.1.32 phosphatidic acid + H2O
-
 Homo sapiens 2-acyl-lysophosphatidic acid + a carboxylate
-
 ?
3.1.1.32 phosphatidic acid + H2O best substrate Homo sapiens 2-acyl-lysophosphatidic acid + a carboxylate
-
 ?
3.1.1.32 phosphatidylcholine + H2O
-
 Homo sapiens 2-acylglycerophosphocholine + a carboxylate
-
 ?
3.1.1.32 phosphatidylcholine + H2O very low activity Homo sapiens 2-acylglycerophosphocholine + a carboxylate
-
 ?
3.1.1.32 phosphatidylethanolamine + H2O similar activity as with phosphatidic acid Homo sapiens 2-acylglycerophosphoethanolamine + a carboxylate
-
 ?
3.1.1.32 phosphatidylserine + H2O low activity Homo sapiens 2-acylglycerophosphoserine + a carboxylate
-
 ?

Subunits

EC Number Subunits Comment Organism
3.1.1.32 ? x * 90000, SDS-PAGE, immunoblot Homo sapiens

Synonyms

EC Number Synonyms Comment Organism
3.1.1.32 PA-PLA1
-
 Homo sapiens
3.1.1.32 phosphatidic acid-preferring phospholipase A1
-
 Homo sapiens