Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Hueros, G.; Rahfeld, J.; Salamini, F.; Thompson, R.
    A maize FK506-sensitive immunophilin, mzFKBP-66, is a peptidylproline cis-trans-isomerase that interacts with calmodulin and a 36-kDa cytoplasmic protein (1998), Planta, 205, 121-131.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
5.2.1.8 expression in Escherichia coli Zea mays

Inhibitors

EC Number Inhibitors Comment Organism Structure
5.2.1.8 FK506 IC50: 110 nM Zea mays

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
5.2.1.8 cytosol
-
 Zea mays 5829
-
5.2.1.8 nucleus
-
 Zea mays 5634
-

Organism

EC Number Organism UniProt Comment Textmining
5.2.1.8 Zea mays
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5.2.1.8 N-succinyl-Ala-Ala-(trans)-Pro-Phe-4-nitroanilide
-
 Zea mays N-succinyl-Ala-Ala-(cis)-Pro-Phe-4-nitroanilide
-
 ?
5.2.1.8 N-succinyl-Ala-Leu-(trans)-Pro-Phe-4-nitroanilide
-
 Zea mays N-succinyl-Ala-Leu-(cis)-Pro-Phe-4-nitroanilide
-
 ?
5.2.1.8 N-succinyl-Ala-Phe-(trans)-Pro-Phe-4-nitroanilide
-
 Zea mays N-succinyl-Ala-Phe-(cis)-Pro-Phe-4-nitroanilide
-
 ?

Synonyms

EC Number Synonyms Comment Organism
5.2.1.8 mzFKBP-66
-
 Zea mays
5.2.1.8 Rotamase
-
 Zea mays

IC50 Value

EC Number IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
5.2.1.8 0.00011
-
 IC50: 110 nM Zea mays FK506