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Literature summary extracted from

  • Woo, W.H.; Yang, H.; Wong, K.P.; Halliwell, B.
    Sulphite oxidase gene expression in human brain and in other human and rat tissues (2003), Biochem. Biophys. Res. Commun., 305, 619-623.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.8.3.1 sulfite + O2 + H2O Homo sapiens lack of active enzyme produces severe neurodegeneration and early death in humans sulfate + H2O2
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.8.3.1 Homo sapiens
-
-
-
1.8.3.1 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.8.3.1 brain
-
 Rattus norvegicus
-
1.8.3.1 brain expression in all brain regions examined: cerebellum, cerebral cortex, medulla, spinal cord, ocipital pole, frontal lobe, amygdala, caudate nucleus, corpus callosum, hippocampus, thalamus, temporal lobe, putamen. The cerebral cortex shows the highest level of expression Homo sapiens
-
1.8.3.1 colon little expression Homo sapiens
-
1.8.3.1 heart
-
 Rattus norvegicus
-
1.8.3.1 heart substantial expression Homo sapiens
-
1.8.3.1 kidney
-
 Rattus norvegicus
-
1.8.3.1 kidney substantial expression Homo sapiens
-
1.8.3.1 leukocyte perpheral blood, little expression Homo sapiens
-
1.8.3.1 liver strong activity Rattus norvegicus
-
1.8.3.1 liver substantial expression Homo sapiens
-
1.8.3.1 lung
-
 Rattus norvegicus
-
1.8.3.1 lung little expression Homo sapiens
-
1.8.3.1 peripheral blood leucocyte, little expression Homo sapiens
-
1.8.3.1 placenta substantial expression Homo sapiens
-
1.8.3.1 skeletal muscle substantial expression Homo sapiens
-
1.8.3.1 small intestine little expression Homo sapiens
-
1.8.3.1 spleen little expression Homo sapiens
-
1.8.3.1 thymus little expression Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.8.3.1 sulfite + O2 + H2O
-
 Homo sapiens sulfate + H2O2
-
 ?
1.8.3.1 sulfite + O2 + H2O
-
 Rattus norvegicus sulfate + H2O2
-
 ?
1.8.3.1 sulfite + O2 + H2O lack of active enzyme produces severe neurodegeneration and early death in humans Homo sapiens sulfate + H2O2
-
 ?