EC Number | Protein Variants | Comment | Organism |
---|---|---|---|
1.8.1.9 | C489S | mutant is incapable of reducing thioredoxin and can only be reduced to the 2-electron-state of enzyme | Drosophila melanogaster |
1.8.1.9 | C489S/C490S | mutant is incapable of reducing thioredoxin and can only be reduced to the 2-electron-state of enzyme | Drosophila melanogaster |
1.8.1.9 | C490S | mutant is incapable of reducing thioredoxin and can only be reduced to the 2-electron-state of enzyme | Drosophila melanogaster |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.8.1.9 | Drosophila melanogaster | - |
- |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.8.1.9 | NADPH + thioredoxin disulfide | mechanism, Cys57 attacks Cys490 in the interchange reaction between the N-terminal dithiol and the C-terminal disulfide | Drosophila melanogaster | NADP+ + thioredoxin | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.8.1.9 | DmTrxR-1 | - |
Drosophila melanogaster |
1.8.1.9 | thioredoxin reductase-1 | - |
Drosophila melanogaster |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.8.1.9 | NADPH | - |
Drosophila melanogaster |