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Literature summary extracted from

  • Cutler, A.J.; Rose, P.A.; Squires, T.M.; Loewen, M.K.; Shaw, A.C.; Quail, J.W.; Krochko, J.E.; Abrams, S.R.
    Inhibitors of abscisic acid 8'-hydroxylase (2000), Biochemistry, 39, 13614-13624.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.14.14.137 (+)-1'-methoxy-abscisate competitive Zea mays
1.14.14.137 (+)-8'-acetylene-abscisate suicide inhibitor Zea mays
1.14.14.137 (+)-8'-cyano-abscisic acid competitive Zea mays
1.14.14.137 (+)-8'-ethyl-abscisic acid competitive Zea mays
1.14.14.137 (+)-8'-methylacetylene-abscisic acid competitive Zea mays
1.14.14.137 (+)-8'-methylene-abscisate competitive Zea mays
1.14.14.137 (+)-8'-propargyl-abscisate competitive Zea mays
1.14.14.137 (+)-9'-allyl-abscisate suicide inhibitor Zea mays
1.14.14.137 (+)-9'-propargyl-abscisate suicide inhibitor Zea mays
1.14.14.137 (-)-8'-propargyl-abscisate competitive Zea mays
1.14.14.137 (-)-9'-propargyl-abscisate suicide inhibitor Zea mays

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.14.14.137 0.016
-
 (+)-S-abscisate pH 7.6, 30°C Zea mays

Organism

EC Number Organism UniProt Comment Textmining
1.14.14.137 Zea mays
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.14.14.137 cell suspension culture
-
 Zea mays
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.14.137 (+)-S-abscisate + [reduced NADPH-hemoprotein reductase] + O2
-
 Zea mays 8'-hydroxyabscisate + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
1.14.14.137 0.00027
-
 (+)-9'-propargyl-abscisate pH 7.6, 30°C Zea mays
1.14.14.137 0.0011
-
 (+)-8'-propargyl-abscisate pH 7.6, 30°C Zea mays
1.14.14.137 0.0055
-
 (+)-9'-allyl-abscisate pH 7.6, 30°C Zea mays
1.14.14.137 0.0111
-
 (+)-1'-methoxy-abscisate pH 7.6, 30°C Zea mays
1.14.14.137 0.0129
-
 (+)-8'-ethyl-abscisic acid pH 7.6, 30°C Zea mays
1.14.14.137 0.0135
-
 (-)-9'-propargyl-abscisate pH 7.6, 30°C Zea mays
1.14.14.137 0.019
-
 (+)-8'-acetylene-abscisate pH 7.6, 30°C Zea mays
1.14.14.137 0.056
-
 (-)-8'-propargyl-abscisate pH 7.6, 30°C Zea mays
1.14.14.137 0.122
-
 (+)-8'-methylene-abscisate pH 7.6, 30°C Zea mays
1.14.14.137 0.187
-
 (+)-8'-cyano-abscisic acid pH 7.6, 30°C Zea mays
1.14.14.137 0.284
-
 (+)-8'-methylacetylene-abscisic acid pH 7.6, 30°C Zea mays