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Literature summary extracted from

  • Danilczyk, U.; Eriksson, U.; Oudit, G.Y.; Penninger, J.M.
    Physiological roles of angiotensin-converting enzyme 2 (2004), Cell. Mol. Life Sci., 61, 2714-2719.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.17.23 additional information Homo sapiens the enzyme has a function in blood pressure regulation, blood flow and fluid regulation. Loss of ACE2 impairs heart function ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.4.17.23 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.17.23 blood vessel cardiac blood vessel Homo sapiens
-
3.4.17.23 heart
-
 Homo sapiens
-
3.4.17.23 kidney tubular epithelium Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.17.23 angiotensin I + H2O
-
 Homo sapiens angiotensin-(1-9) + Leu
-
 ?
3.4.17.23 angiotensin II + H2O
-
 Homo sapiens angiotensin-(1-7) + Phe
-
 ?
3.4.17.23 apelin-13 + H2O
-
 Homo sapiens QRPRLSHKGPMP + Phe
-
 ?
3.4.17.23 apelin-36 + H2O
-
 Homo sapiens ?
-
 ?
3.4.17.23 beta-casomorphin + H2O
-
 Homo sapiens YPFVEP + Ile
-
 ?
3.4.17.23 des-Arg9-bradykinin + H2O
-
 Homo sapiens RPPGFSP + Phe
-
 ?
3.4.17.23 dynorphin A(1-13) + H2O
-
 Homo sapiens YGGFLRRIRPKL + Lys
-
 ?
3.4.17.23 Lys-des-Arg9 bradykinin + H2O
-
 Homo sapiens KRPPGFSP + Phe
-
 ?
3.4.17.23 additional information the enzyme has a function in blood pressure regulation, blood flow and fluid regulation. Loss of ACE2 impairs heart function Homo sapiens ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.4.17.23 ACE2
-
 Homo sapiens