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Literature summary extracted from

  • Fujimoto, Y.; Onoduka, J.; Homma, K.J.; Yamaguchi, S.; Mori, M.; Higashi, Y.; Makita, M.; Kinoshita, T.; Noda, J.; Itabe, H.; Takanoa, T.
    Long-chain fatty acids induce lipid droplet formation in a cultured human hepatocyte in a manner dependent of acyl-CoA synthetase (2006), Biol. Pharm. Bull., 29, 2174-2180.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
6.2.1.3 additional information not inhibited by 4,4,10 beta-trimethyl-trans-decal-3 beta-ol Homo sapiens
6.2.1.3 Triacsin C significant inhibition Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining

Organism

EC Number Organism UniProt Comment Textmining
6.2.1.3 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
6.2.1.3 hepatocyte
-
 Homo sapiens
-
6.2.1.3 Huh-7 cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.2.1.3 ATP + laurate + CoA
-
 Homo sapiens AMP + diphosphate + lauroyl-CoA
-
 ?
6.2.1.3 ATP + linoleate + CoA
-
 Homo sapiens AMP + diphosphate + linoleoyl-CoA
-
 ?
6.2.1.3 ATP + myristate + CoA
-
 Homo sapiens AMP + diphosphate + myristoyl-CoA
-
 ?
6.2.1.3 ATP + oleate + CoA
-
 Homo sapiens AMP + diphosphate + oleoyl-CoA
-
 ?
6.2.1.3 ATP + palmitate + CoA
-
 Homo sapiens AMP + diphosphate + palmitoyl-CoA
-
 ?
6.2.1.3 ATP + stearate + CoA
-
 Homo sapiens AMP + diphosphate + stearoyl-CoA
-
 ?
6.2.1.3 additional information octanoate and decanoate are ineffective substrates Homo sapiens ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
6.2.1.3 long chain acyl-CoA synthetase
-
 Homo sapiens

Cofactor

EC Number Cofactor Comment Organism Structure
6.2.1.3 ATP
-
 Homo sapiens