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Literature summary extracted from

  • Kass, D.; Bridges, R.S.; Borczuk, A.; Greenberg, S.
    Methionine aminopeptidase-2 as a selective target of myofibroblasts in pulmonary fibrosis (2007), Am. J. Respir. Cell Mol. Biol., 37, 193-201.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.11.18 fumagillin irreversible inhibition Homo sapiens
3.4.11.18 fumagillin irreversible inhibition Mus musculus
3.4.11.18 fumagillin irreversible inhibition Rattus norvegicus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.11.18 Met-peptide + H2O Homo sapiens
-
 Met + peptide
-
 ?
3.4.11.18 Met-peptide + H2O Mus musculus
-
 Met + peptide
-
 ?
3.4.11.18 Met-peptide + H2O Rattus norvegicus
-
 Met + peptide
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.4.11.18 Homo sapiens P50579
-
-
3.4.11.18 Mus musculus O08663
-
-
3.4.11.18 Rattus norvegicus P38062
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.11.18 fibroblast
-
 Rattus norvegicus
-
3.4.11.18 lung
-
 Homo sapiens
-
3.4.11.18 lung
-
 Mus musculus
-
3.4.11.18 lung
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.11.18 Met-peptide + H2O
-
 Homo sapiens Met + peptide
-
 ?
3.4.11.18 Met-peptide + H2O
-
 Mus musculus Met + peptide
-
 ?
3.4.11.18 Met-peptide + H2O
-
 Rattus norvegicus Met + peptide
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.4.11.18 MetAP2
-
 Homo sapiens
3.4.11.18 MetAP2
-
 Mus musculus
3.4.11.18 MetAP2
-
 Rattus norvegicus
3.4.11.18 methionine aminopeptidase-2
-
 Homo sapiens
3.4.11.18 methionine aminopeptidase-2
-
 Mus musculus
3.4.11.18 methionine aminopeptidase-2
-
 Rattus norvegicus