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Literature summary extracted from

  • Esposito, L.; Sica, F.; Raia, C.A.; Giordano, A.; Rossi, M.; Mazzarella, L.; Zagari, A.
    Crystal structure of the alcohol dehydrogenase from the hyperthermophilic archaeon Sulfolobus solfataricus at 1.85 A resolution (2002), J. Mol. Biol., 318, 463-477.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.1.1.1 expressed in Escherichia coli RB791 cells Saccharolobus solfataricus

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
1.1.1.1 microbatch method in 100 mM Tris-HCl (pH 7.8), 10 mM dithiotreitol with the same volume of 12% (w/v) PEG 4000, 12% (v/v) 2-propanol, 100 mM sodium citrate (pH 5.6) at 20°C Saccharolobus solfataricus

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
1.1.1.1 Zn2+ zinc-containing enzyme Saccharolobus solfataricus

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.1 Saccharolobus solfataricus P39462
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.1.1.1
-
 Saccharolobus solfataricus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.1 ethanol + NAD+
-
 Saccharolobus solfataricus acetaldehyde + NADH + H+
-
 ?

Subunits

EC Number Subunits Comment Organism
1.1.1.1 dimer dimer of dimers, X-ray crystallography Saccharolobus solfataricus
1.1.1.1 homotetramer x-ray crystallography Saccharolobus solfataricus

Synonyms

EC Number Synonyms Comment Organism
1.1.1.1 ADH
-
 Saccharolobus solfataricus

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.1 NAD+
-
 Saccharolobus solfataricus
1.1.1.1 NADH
-
 Saccharolobus solfataricus