Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Condo, I.; Ruggero, D.; Reinhardt, R.; Londei, P.
    A novel aminopeptidase associated with the 60 kDa chaperonin in the thermophilic archaeon Sulfolobus solfataricus (1998), Mol. Microbiol., 29, 775-785.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.4.11.B3
-
 Saccharolobus solfataricus

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.11.B3 EDTA 1 mM, complete inhibition Saccharolobus solfataricus
3.4.11.B3 additional information puromycin shows weak inhibitory effect Saccharolobus solfataricus

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.4.11.B3 Zn2+ zinc-dependent enzyme Saccharolobus solfataricus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.4.11.B3 90000
-
 x * 90000, SDS-PAGE Saccharolobus solfataricus

Organism

EC Number Organism UniProt Comment Textmining
3.4.11.B3 Saccharolobus solfataricus P95928
-
-
5.6.1.7 Saccharolobus solfataricus
-
-
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
3.4.11.B3 phosphoprotein
-
 Saccharolobus solfataricus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.11.B3 L-alanyl 4-nitroanilide + H2O about 70% of the activity compared to L-leucyl 4-nitroanilide Saccharolobus solfataricus L-alanine + 4-nitroaniline
-
 ?
3.4.11.B3 L-arginyl 4-nitroanilide + H2O about 30% of the activity compared to L-leucyl 4-nitroanilide Saccharolobus solfataricus L-arginine + 4-nitroaniline
-
 ?
3.4.11.B3 L-leucyl 4-nitroanilide + H2O
-
 Saccharolobus solfataricus L-leucine + 4-nitroaniline
-
 ?
3.4.11.B3 L-lysyl 4-nitroanilide + H2O about 15% of the activity compared to L-leucyl 4-nitroanilide Saccharolobus solfataricus L-lysine + 4-nitroaniline
-
 ?
3.4.11.B3 L-methionyl 4-nitroanilide + H2O about 70% of the activity compared to L-leucyl 4-nitroanilide Saccharolobus solfataricus L-methionine + 4-nitroaniline
-
 ?
3.4.11.B3 L-phenylalanyl 4-nitroanilide + H2O about 35% of the activity compared to L-leucyl 4-nitroanilide Saccharolobus solfataricus L-phenylalanine + 4-nitroaniline
-
 ?
3.4.11.B3 L-prolyl 4-nitroanilide + H2O about 20% of the activity compared to L-leucyl 4-nitroanilide Saccharolobus solfataricus L-proline + 4-nitroaniline
-
 ?

Subunits

EC Number Subunits Comment Organism
3.4.11.B3 ? x * 90000, SDS-PAGE Saccharolobus solfataricus
5.6.1.7 More enzyme interacts with several proteins other than the two subunits that constitute the 18mer double ring structure. One of these proteins is a zinc-dependent aminopeptidase of 90 kDa which contains a leucine zipper motif and can be phosphorylated Saccharolobus solfataricus

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
3.4.11.B3 80
-
-
 Saccharolobus solfataricus

Temperature Range [°C]

EC Number Temperature Minimum [°C] Temperature Maximum [°C] Comment Organism
3.4.11.B3 80 95 80°C: optimum, 95°C: 40% of maximal activity, no activity below 30°C Saccharolobus solfataricus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.4.11.B3 6
-
-
 Saccharolobus solfataricus

pH Range

EC Number pH Minimum pH Maximum Comment Organism
3.4.11.B3 5 7
-
 Saccharolobus solfataricus