EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
1.17.3.2 | 0.00046 | - |
6-Thioxanthine | 25°C | Bos taurus | |
1.17.3.2 | 0.00047 | - |
2-Thioxanthine | 25°C | Bos taurus | |
1.17.3.2 | 0.00088 | - |
2-mercaptopurine | 25°C | Bos taurus | |
1.17.3.2 | 0.002 | - |
6-Mercaptopurine | 25°C | Bos taurus |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.17.3.2 | xanthine + H2O + O2 | Bos taurus | - |
urate + H2O2 | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.17.3.2 | Bos taurus | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
1.17.3.2 | milk | - |
Bos taurus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.17.3.2 | 2-mercaptopurine + H2O + O2 | no conversion to 2-thioxanthine | Bos taurus | 8-hydroxy-2-mercaptopurine + H2O2 | - |
? | |
1.17.3.2 | 2-thioxanthine + H2O + O2 | - |
Bos taurus | 2-thiouric acid + H2O2 | - |
? | |
1.17.3.2 | 6-mercaptopurine + 2 H2O + 2 O2 | a two-step reaction with 6-thioxanthine as intermediate | Bos taurus | 6-thiouric acid + 2 H2O2 | - |
? | |
1.17.3.2 | 6-thioxanthine + H2O + O2 | - |
Bos taurus | 6-thiouric acid + H2O2 | - |
? | |
1.17.3.2 | hypoxanthine + 2 H2O + 2 O2 | a two-step reaction with xanthine as intermediate, production of superoxide radicals | Bos taurus | urate + 2 H2O2 | - |
? | |
1.17.3.2 | additional information | nature and position of functional group on thiopurine substrates influence activity of xanthine oxidase | Bos taurus | ? | - |
? | |
1.17.3.2 | xanthine + H2O + O2 | - |
Bos taurus | urate + H2O2 | - |
? | |
1.17.3.2 | xanthine + H2O + O2 | production of superoxide radicals | Bos taurus | urate + H2O2 | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.17.3.2 | XOD | - |
Bos taurus |
EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|---|
1.17.3.2 | 25 | - |
assay at | Bos taurus |
EC Number | Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
1.17.3.2 | 0.13 | - |
6-Mercaptopurine | 25°C | Bos taurus | |
1.17.3.2 | 1.98 | - |
2-mercaptopurine | 25°C | Bos taurus | |
1.17.3.2 | 2.76 | - |
6-Thioxanthine | 25°C | Bos taurus | |
1.17.3.2 | 3.32 | - |
2-Thioxanthine | 25°C | Bos taurus |