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Literature summary extracted from

  • Li Volti, G.; Sorrenti, V.; Murabito, P.; Galvano, F.; Veroux, M.; Gullo, A.; Acquaviva, R.; Stacchiotti, A.; Bonomini, F.; Vanella, L.; Di Giacomo, C.
    Pharmacological induction of heme oxygenase-1 inhibits iNOS and oxidative stress in renal ischemia-reperfusion injury (2007), Transplant. Proc., 39, 2986-2991.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
1.14.14.18 SnCl2 is a potent and specific inducer of renal HO-1 expression and activity Rattus norvegicus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.14.14.18 heme + AH2 + O2 Rattus norvegicus
-
 biliverdin + Fe2+ + CO + A + H2O
-
 ?
1.14.14.18 additional information Rattus norvegicus HO-1 and its byproduct biliverdin play major roles in the pathophysiological cascade leading to renal I/R injury ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.14.14.18 Rattus norvegicus P06762
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.14.14.18 kidney HO-1 and HO-2 contents, immunohistochemic analysis, overview Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.14.18 heme + AH2 + O2
-
 Rattus norvegicus biliverdin + Fe2+ + CO + A + H2O
-
 ?
1.14.14.18 additional information HO-1 and its byproduct biliverdin play major roles in the pathophysiological cascade leading to renal I/R injury Rattus norvegicus ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.14.14.18 heme oxygenase-1
-
 Rattus norvegicus
1.14.14.18 heme oxygenase-2
-
 Rattus norvegicus
1.14.14.18 HO-1
-
 Rattus norvegicus
1.14.14.18 HO-2
-
 Rattus norvegicus