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Literature summary extracted from

  • Sun, Z.; Carpiaux, W.; Fan, D.; Fan, Y.; Lakshminarayanan, R.; Moradian-Oldak, J.
    Apatite reduces amelogenin proteolysis by MMP-20 and KLK4 in vitro (2010), J. Dent. Res., 89, 344-348.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.4.24.B6 expression of His-tagged MMP-20 Sus scrofa

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.24.B6 hydroxyapatite
-
 Sus scrofa

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.4.24.B6 extracellular matrix
-
 Sus scrofa 31012
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.24.B6 amelogenin + H2O Sus scrofa amelogenin constitutes more than 90% of enamel extracellular matrix proteins in secretory-stage enamel ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.4.24.B6 Sus scrofa
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.4.24.B6 recombinant His-tagged MMP-20 by metal affinity chromatography Sus scrofa

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.24.B6 enamel layer MMP-20 is expressed in the secretory stage Sus scrofa
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.24.B6 amelogenin + H2O
-
 Sus scrofa ?
-
 ?
3.4.24.B6 amelogenin + H2O amelogenin constitutes more than 90% of enamel extracellular matrix proteins in secretory-stage enamel Sus scrofa ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.4.24.B6 enamelysin
-
 Sus scrofa
3.4.24.B6 MMP-20
-
 Sus scrofa

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
3.4.24.B6 37
-
 assay at Sus scrofa

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.4.24.B6 8
-
 assay at Sus scrofa

General Information

EC Number General Information Comment Organism
3.4.24.B6 physiological function the enamel protease MMP-20 cleaves amelogenin and is necessary for proper enamel formation. Matrix-mediated enamel biomineralization involves concurrent processes of enamel matrix protein degradation and hydroxyapatite maturation Sus scrofa